Results 71 to 80 of about 14,201,582 (335)

A neutral theory of genome evolution and the frequency distribution of genes

BMC Genomics, 2012
Background The gene composition of bacteria of the same species can differ significantly between isolates. Variability in gene composition can be summarized in terms of gene frequency distributions, in which individual genes are ranked according to the ...
Haegeman Bart, Weitz Joshua S
doaj   +1 more source

Gene-Mating Dynamic Evolution Theory II: Global stability of N-gender-mating polyploid systems

, 2020
Extending the previous 2-gender dioecious diploid gene-mating evolution model [arXiv:1410.3456], we attempt to answer "whether the Hardy-Weinberg global stability and the exact analytic dynamical solutions can be found in the generalized N-gender N ...
Wang, Juven
core   +1 more source

Serological and RHD genotyping characteristics of RhD-negative populations in primary screening in Beijing

Zhongguo shuxue zazhi
Objective To study the RHD genotyping of primary screening RhD negative population in Beijing, and analyze the serological characteristics of different genotypes and the distribution of Rh phenotypes.
Ke SONG, Chunya MA, Yuanyuan LUO, Yang YU   +3 more
doaj   +1 more source

Growth Hormone Gene Polymorphism and Its Association with Partial Cumulative Milk Yields of Holstein Friesian Dairy Cattle [PDF]

, 2012
Growth hormone gene (GH gene) plays an important role in regulating body growth and in developing mammary gland, similar with its interaction to specific receptors.
Andreas, E. (E), Anggraeni, A. (A), Misrianti, R. (R), Sumantri, C. (C)   +3 more
core  

Spatial gene drives and pushed genetic waves

, 2017
Gene drives have the potential to rapidly replace a harmful wild-type allele with a gene drive allele engineered to have desired functionalities. However, an accidental or premature release of a gene drive construct to the natural environment could ...
Nelson, David R., Stone, Howard A., Tanaka, Hidenori   +2 more
core   +1 more source

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo [PDF]

, 2007
We treated 10 children with X-linked SCID (SCID-X1) using gammaretrovirus-mediated gene transfer. Those with sufficient follow-up were found to have recovered substantial immunity in the absence of any serious adverse events up to 5 years after treatment.
Kerstin Schwarzwaelder, Steven J. Howe, Manfred Schmidt, Martijn H. Brugman, Annette Deichmann, Hanno Glimm, Sonja Schmidt, Claudia Prinz, Manuela Wissler, Douglas J.S. King, Fang Zhang, Kathryn L. Parsley, Kimberly C. Gilmour, Joanna Sinclair, Jinhua Bayford, Rachel Peraj, Karin Pike-Overzet, Frank J.T. Staal, Dick de Ridder, Christine Kinnon, Ulrich Abel, Gerard Wagemaker, H. Bobby Gaspar, Adrian J. Thrasher, Christof von Kalle, Cavazzana-Calvo, Gaspar, Hacein-Bey-Abina, Aiuti, Aiuti, Gaspar, Ott, Hacein-Bey-Abina, Li, Kustikova, Modlich, Montini, Mitchell, Schröder, Wu, Bushman, Schmidt, Schmidt, Hematti, Laufs, Suzuki, Bartholomew, Recchia, Calmels, Hoeben, Palmer, Xu, Dik, Ge   +53 more
core   +2 more sources

Gene duplication and evolution in recurring polyploidization–diploidization cycles in plants

Genome Biology, 2019
The sharp increase of plant genome and transcriptome data provide valuable resources to investigate evolutionary consequences of gene duplication in a range of taxa, and unravel common principles underlying duplicate gene retention.
Xin Qiao, Qionghou Li, Hao Yin, K. Qi, Leiting Li, Runze Wang, Shaoling Zhang, A. Paterson   +7 more
semanticscholar   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

On the number of ranked species trees producing anomalous ranked gene trees

, 2014
Analysis of probability distributions conditional on species trees has demonstrated the existence of anomalous ranked gene trees (ARGTs), ranked gene trees that are more probable than the ranked gene tree that accords with the ranked species tree.
Disanto, Filippo, Rosenberg, Noah A.
core   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source