Results 201 to 210 of about 6,900,738 (371)

cDNA Cloning of Myosin Heavy Chain Isoforms From Carp Fast Skeletal Muscle and Their Gene Expression Associated With Temperature Acclimation [PDF]

, 1997
Junichi Imai, Yasushi Hirayama, Kiyoshi Kikuchi, Makoto Kakinuma, Shugo Watabe   +4 more
openalex   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

The η Isoform of Protein Kinase C Mediates Transcriptional Activation of the Human Transglutaminase 1 Gene [PDF]

, 1996
Eiichiro Ueda, Shigeo Ohno, Toshio Kuroki, Etta Livneh, Keiko Yamada, K Yamanishi, Hirokazu Yasuno   +6 more
openalex   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Genomic Organization of the Mouse and Human Genes Encoding the ATP Sulfurylase/Adenosine 5′-Phosphosulfate Kinase Isoform SK2 [PDF]

, 1999
Kiyoto Kurima, Bhawani Singh, Nancy B. Schwartz   +2 more
openalex   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source

Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6).

, 1990
T. Kayano, Charles Burant, Hirofumi Fukumoto, Gwyn W. Gould, Yao Fan, Roger L. Eddy, M.G. Byers, T.B. Shows, Susumu Seino, G I Bell   +9 more
openalex   +1 more source

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source

Cloning and Characterization of Novel Isoforms of the BOULE Gene in Bats [PDF]

Biochemical Genetics, 2009
Paul A. Racey, Lihong Yuan, Eran Levin, Xueguo Zuo, Lingjiang He, Shuyi Zhang   +5 more
openaire   +3 more sources

Gene expression for two glutathione transferase isoforms in placenta of women from Ukraine regions with various radioactive pollution [PDF]

, 1997
Victor Prima, N. A. Melnik, E. I. Martynenko, Galyna Bartish, Tatyana Tchaikovskaya, M. Yu. Obolenskaya   +5 more
openalex   +1 more source