Differential Characteristics and Subcellular Localization of Two Starch-branching Enzyme Isoforms Encoded by a Single Gene inPhaseolus vulgaris L. [PDF]
Shigeki Hamada+8 more
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β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong+15 more
wiley +1 more source
Delta-catenin is required for cell proliferation in virus-positive Merkel cell carcinoma cell lines but not in human fibroblasts. [PDF]
Landazuri Vinueza J+4 more
europepmc +1 more source
Biosynthesis of UDP-Xylose. Cloning and Characterization of a Novel Arabidopsis Gene Family, UXS, Encoding Soluble and Putative Membrane-Bound UDP-Glucuronic Acid Decarboxylase Isoforms [PDF]
April D. Harper, Maor Bar‐Peled
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FM‐DEL1 and FM‐DEL2 are constructed by installing one or two sets of building blocks on a phenylalanine central scaffold. FM‐DELs are screened against markers of prostate, and renal cell carcinoma, and against an immunological target expressed on the surface of natural killer cells.
Francesca Migliorini+12 more
wiley +1 more source
Heat shock induces alternative polyadenylation through dynamic DNA methylation and chromatin looping. [PDF]
Fink EE+7 more
europepmc +1 more source
BRD4 Signaling Maintains the Differentiated State of β Cells
The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
Fuqiang Liu+22 more
wiley +1 more source
Alternative transcription increases isoform complexity in Long Non-Coding RNAs and alters their functions in cancer. [PDF]
Bone M, Inman GJ.
europepmc +1 more source