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Prioritizing genes with functionally distinct splice isoforms
2020Most mammalian genes generate multiple transcripts via splicing, and we do not know the function of most splice variants. Currently, there is a debate about how many splice variants are likely nonfunctional or “noisy” transcripts. My thesis explores the claim that alternative splicing vastly increases the genome’s functional diversity in the context of
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isoISG - isoforms of Interferon-Stimulated Genes
Welcome to the isoISG entry This entry serves as a source of annotation data, scripts, and supplementary data for our paper titled "Functional and Dynamic Profiling of Transcript Isoforms Reveals Essential Roles of Alternative Splicing in Interferon Response." In this study, we generated a novel isoform annotation for IFN-α-stimulated and ...openaire +1 more source
Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
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Horizontal gene transfer and adaptive evolution in bacteria
Nature Reviews Microbiology, 2021Brian J Arnold, William P Hanage
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Beyond horizontal gene transfer: the role of plasmids in bacterial evolution
Nature Reviews Microbiology, 2021Jerónimo Rodríguez-Beltrán +2 more
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Nanooncology: The future of cancer diagnosis and therapy
Ca-A Cancer Journal for Clinicians, 2013Sanjiv S Gambhir
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Gene regulation by long non-coding RNAs and its biological functions
Nature Reviews Molecular Cell Biology, 2020Luisa Statello +2 more
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