Results 301 to 310 of about 6,900,738 (371)

Alternative Splicing in Tumorigenesis and Cancer Therapy. [PDF]

Biomolecules
Chen H, Tang J, Xiang J.
europepmc   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source

Mutation screening at the RNA level of theSTK11/LKB1gene in Peutz-Jeghers syndrome reveals complex splicing abnormalities and a novel mRNA isoform (STK11c.597^⁁598insIVS4)

, 2001
Abdalla A. Abed, Klaus Günther, Cornelia Kraus, Werner Hohenberger, Wolfgang G. Ballhausen   +4 more
openalex   +1 more source

Benefit from Biomass Boiler Emissions to Increase Greenhouse CO2 Levels for Optimal Growth and Yield in Tomato, Cucumber, and Strawberry

Advanced Energy and Sustainability Research, EarlyView.
Using CO2‐rich polluting gases in greenhouse plant cultivation has proven to be a promising technique for stimulating plants while reducing emissions to the atmosphere. The use of an experimental biofilter proves to be effective in retaining most of the toxic particles. The alteration of physiological and metabolic parameters shows an adaptation of the
Alberto Martinez‐Alonso, Jose Fermoso, Francisco Verdugo, Micaela Carvajal   +3 more
wiley   +1 more source

<i>PIK3R1</i> and <i>G0S2</i> are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation. [PDF]

Epigenetics
Daskeviciute D, Sainty B, Chappell-Maor L, Bone C, Russell S, Iglesias-Platas I, Arnaud P, Monteagudo-Sánchez A, Greenberg MVC, Chen K, Manerao-Azua A, Perez de Nanclares G, Lartey J, Monk D.   +13 more
europepmc   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source

Constraints on the optimization of gene product diversity. [PDF]

Mol Syst Biol
Jiang D, Kejiou N, Qiu Y, Palazzo AF, Pennell M.   +4 more
europepmc   +1 more source

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

Discovery of novel conserved peptide domains by ortholog comparison within plant multi-protein families [PDF]

, 2005
Panstruga, R.
core   +1 more source

A novel isoform of human lymphoid enhancer-binding factor-1 (LEF-1) gene transcript encodes a protein devoid of HMG domain and nuclear localization signal.

, 2001
Agnieszka Kobielak, Krzysztof Kobielak, W H Trzeciak   +2 more
openalex   +2 more sources