Results 11 to 20 of about 681,317 (262)
Adventures in the enormous: a 1.8 million clone BAC library for the 21.7 Gb genome of loblolly pine. [PDF]
PLoS ONE, 2011 Loblolly pine (LP; Pinus taeda L.) is the most economically important tree in the U.S. and a cornerstone species in southeastern forests. However, genomics research on LP and other conifers has lagged behind studies on flowering plants due, in part, to ...
Zenaida V Magbanua +8 more
doaj +1 more source
The COVID-19 Gene and Drug Set Library [PDF]
SSRN Electronic Journal, 2020 Abstract The coronavirus (CoV) severe acute respiratory syndrome (SARS)-CoV-2 (COVID-19) pandemic has received rapid response by the research community to offer suggestions for repurposing of approved drugs as well as to improve our understanding of the COVID-19 viral life cycle molecular mechanisms.
Maxim V. Kuleshov +9 more
openaire +3 more sources
Preparation of trinucleotide phosphoramidites as synthons for the synthesis of gene libraries
Beilstein Journal of Organic Chemistry, 2018 The preparation of protein libraries is a key issue in protein engineering and biotechnology. Such libraries can be prepared by a variety of methods, starting from the respective gene library.
Ruth Suchsland +2 more
doaj +1 more source
Analysis of shuffled gene libraries
Journal of Molecular Biology, 2002 In vitro recombination of homologous genes (family shuffling) has been proposed as an effective search strategy for laboratory evolution of genes and proteins. Few data are available, however, on the composition of shuffled gene libraries, from which one could assess the efficiency of recombination and optimize protocols.
Joern, John M +2 more
openaire +3 more sources
Synthetic and Systems Biotechnology, 2017 Engineering cell factories for producing biofuels and pharmaceuticals has spurred great interests to develop rapid and efficient synthetic biology tools customized for modular pathway engineering.
Erqing Jin +5 more
doaj +1 more source
Mutant non-coding RNA resource in mouse embryonic stem cells
Disease Models & Mechanisms, 2021 Gene trapping is a high-throughput approach that has been used to introduce insertional mutations into the genome of mouse embryonic stem (ES) cells. It is performed with generic gene trap vectors that simultaneously mutate and report the expression of ...
Jens Hansen +2 more
doaj +1 more source
A high-throughput method for Illumina RNA-Seq library preparation
Frontiers in Plant Science, 2012 With the introduction of cost effective, rapid and superior quality next generation sequencing (NGS) techniques, gene expression analysis has become viable for labs conducting small projects as well as large-scale gene expression analysis experiments ...
Ravi eKumar +8 more
doaj +1 more source
Screening technology of cyclic peptide library based on gene encoding
Medicine in Drug Discovery, 2022 As a powerful tool for the discovery of peptide compounds, high-throughput library screening technology can also perform multitarget screening with high chemical diversity as a condition, which accelerates the process of exploring high-affinity peptide ...
Yangqiang Chen +5 more
doaj +1 more source
Cloning of a Transglutaminase Gene from an Indonesian Streptomyces Strain
Squalen, 2016 Microbial Transglutaminase (MTGase, EC 2.3.2.13) is an enzyme that catalyzes the transfer of acyl group. Many microbial strains that produce MTGase belong to Streptomyces members. This research was aimed at cloning of a MTGase gene.
Seprianto Chaniago
doaj +1 more source
Generation and characterization of expressed sequence tags in young roots of tea (Camellia assamica)
Biologia Plantarum, 2016 Assam tea (Camellia assamica) is perennial crop susceptible to moisture stress. We used its tender roots to construct a cDNA library for the identification, functional annotation, and analysis of transcripts. A total of 811 full-length expressed sequence
A. Das, M. Mukhopadhyay, T. K. Mondal
doaj +1 more source