Results 91 to 100 of about 13,329,719 (303)
Losing Genes: The Evolutionary Remodeling of Cetacea Skin
Frontiers in Marine Science, 2020 The skin is a multi-layered organ, often displaying associated structures, that establishes a protective interface between the organism and the surrounding environment.
Gonçalo Espregueira Themudo +8 more
doaj +1 more source
Evolution of substrate specificity in a retained enzyme driven by gene loss
eLife, 2017 The connection between gene loss and the functional adaptation of retained proteins is still poorly understood. We apply phylogenomics and metabolic modeling to detect bacterial species that are evolving by gene loss, with the finding that ...
Ana L. Juárez-Vázquez +14 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Gene loss rate: a probabilistic measure for the conservation of eukaryotic genes [PDF]
Nucleic Acids Research, 2006 The rate of conservation of a gene in evolution is believed to be correlated with its biological importance. Recent studies have devised various conservation measures for genes and have shown that they are correlated with several biological characteristics of functional importance.
Borenstein, Elhanan +3 more
openaire +2 more sources
The invasive MED/Q Bemisia tabaci genome: a tale of gene loss and gene gain
BMC Genomics, 2018 Sweetpotato whitefly, Bemisia tabaci MED/Q and MEAM1/B, are two economically important invasive species that cause considerable damages to agriculture crops through direct feeding and indirect vectoring of plant pathogens.
W. Xie +14 more
semanticscholar +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Gene–diet interaction and weight loss [PDF]
Current Opinion in Lipidology, 2014 The purpose of this review is to summarize recent advances in investigations of dietary factors, genetic factors, and their interactive effects on obesity and weight loss.Even with a tremendous body of research conducted, controversy still abounds regarding the relative effectiveness of various weight-loss diets.
openaire +2 more sources
Current Biology, 2018 Mutation and recombination are main drivers of phenotypic diversity, but the ability to create new allelic combinations is strongly dependent on the mode of reproduction.
C. Rödelsperger +6 more
semanticscholar +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Rapid loss of plastid ndh genes in slipper orchids (Cypripedioideae, Orchidaceae)
Frontiers in Plant ScienceIntroductionThe eleven plastid ndh genes encode for subunits of the ndh (NAD(P)H dehydrogenase-like) complex, which mediates electron flow in photosystem I. The loss of ndh genes in plants was observed in many different lineages of Viridiplantae.
Victoria E. Ringelmann +1 more
doaj +1 more source