Results 81 to 90 of about 13,329,719 (303)
Antivirulence Genes: Insights into Pathogen Evolution through Gene Loss [PDF]
Infection and Immunity, 2012 ABSTRACT The emergence of new pathogens and the exploitation of novel pathogenic niches by bacteria typically require the horizontal transfer of virulence factors and subsequent adaptation—a “fine-tuning” process—for the successful incorporation of these factors into the microbe's genome.
Kimberly A, Bliven, Anthony T, Maurelli
openaire +2 more sources
The ecological adaptation of the unparalleled plastome character evolution in slipper orchids
Frontiers in Plant Science, 2022 Plastomes may have undergone adaptive evolution in the process of plant adaptation to diverse environments, whereby species may differ in plastome characters.
Chao Hu +15 more
doaj +1 more source
progressiveMauve: Multiple Genome Alignment with Gene Gain, Loss and Rearrangement
PLoS ONE, 2010 Background Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms.
A. Darling, B. Mau, N. Perna
semanticscholar +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gene Losses during Human Origins
PLoS Biology, 2006 Pseudogenization is a widespread phenomenon in genome evolution, and it has been proposed to serve as an engine of evolutionary change, especially during human origins (the "less-is-more" hypothesis). However, there has been no comprehensive analysis of human-specific pseudogenes.
Xiaoxia Wang +2 more
openaire +4 more sources
Escape from preferential retention following repeated whole genome duplication in plants
Frontiers in Plant Science, 2012 The well supported gene dosage hypothesis predicts that genes encoding proteins engaged in dose-sensitive interactions cannot be reduced back to single copies once all interacting partners are simultaneously duplicated in a whole genome duplication.
James C Schnable +3 more
doaj +1 more source
The Most Developmentally Truncated Fishes Show Extensive Hox Gene Loss and Miniaturized Genomes
bioRxiv, 2017 Hox genes play a fundamental role in regulating the embryonic development of all animals. Manipulation of these transcription factors in model organisms has unraveled key aspects of evolution, like the transition from fin to limb.
Martin Malmstrøm +9 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Loss of retinoblastoma gene and amplification of N-myc gene in retinoblastoma [PDF]
Journal of Korean Medical Science, 1993 We have analyzed paired samples of genomic DNA from peripheral leukocyte and primary tumor tissue from nine patients with retinoblastoma (RB) and from two RB cell lines, WERI-Rb-1 and Y79, to detect the molecular alterations of the retinoblastoma susceptibility gene (RB-1) and N-myc gene.
S W, Choi +5 more
openaire +2 more sources
Mitochondrial DNA. Part B. Resources, 2020 We here report the complete chloroplast genome of Pedicularis verticillata and the reconstructed chloroplast genome of Pedicularis cheilanthifolia, the first such genome reported for this genus. The P.
Won-Bum Cho +3 more
doaj +1 more source