Results 81 to 90 of about 6,611,862 (305)
A Comprehensive Review on the Biosynthesis of Tropane Alkaloids
MoleculesTropane alkaloids (TA) constitute a class of plant specialized metabolites with important pharmaceutical applications, including the anticholinergic agents hyoscyamine and scopolamine and the local anesthetic cocaine.
Shiyu Wan +4 more
doaj +1 more source
The ecological adaptation of the unparalleled plastome character evolution in slipper orchids
Frontiers in Plant Science, 2022 Plastomes may have undergone adaptive evolution in the process of plant adaptation to diverse environments, whereby species may differ in plastome characters.
Chao Hu +15 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Escape from preferential retention following repeated whole genome duplication in plants
Frontiers in Plant Science, 2012 The well supported gene dosage hypothesis predicts that genes encoding proteins engaged in dose-sensitive interactions cannot be reduced back to single copies once all interacting partners are simultaneously duplicated in a whole genome duplication.
James C Schnable +3 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Parasites lead to evolution of robustness against gene loss in host signaling networks [PDF]
, 2008 Many biological networks can maintain their function against single gene loss. However, the evolutionary mechanisms responsible for such robustness remain unclear.
Orkun S Soyer +3 more
core +1 more source
Antivirulence Genes: Insights into Pathogen Evolution through Gene Loss [PDF]
Infection and Immunity, 2012 ABSTRACT The emergence of new pathogens and the exploitation of novel pathogenic niches by bacteria typically require the horizontal transfer of virulence factors and subsequent adaptation—a “fine-tuning” process—for the successful incorporation of these factors into the microbe's genome.
Kimberly A, Bliven, Anthony T, Maurelli
openaire +2 more sources
Mitochondrial DNA. Part B. Resources, 2020 We here report the complete chloroplast genome of Pedicularis verticillata and the reconstructed chloroplast genome of Pedicularis cheilanthifolia, the first such genome reported for this genus. The P.
Won-Bum Cho +3 more
doaj +1 more source
Losing Genes: The Evolutionary Remodeling of Cetacea Skin
Frontiers in Marine Science, 2020 The skin is a multi-layered organ, often displaying associated structures, that establishes a protective interface between the organism and the surrounding environment.
Gonçalo Espregueira Themudo +8 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source