Results 21 to 30 of about 2,855,271 (302)
Frontiers in Microbiology, 2012 Mercuric mercury (Hg[II]) is a highly toxic and mobile element that is likely to have had a pronounced and adverse effect on biology since Earth’s oxygenation ~2.4 Gy ago due to its high affinity for protein sulfhydryl groups, which upon binding ...
Eric eBoyd, Tamar eBarkay
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Frontiers in Genetics, 2020 The family Orobanchaceae including autotrophic, hemiparasitic, and holoparasitic species, is becoming a key taxa to study the evolution of chloroplast genomes in different lifestyles. But the early evolutionary trajectory in the transit from autotrophism
Ruiting Zhang +8 more
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Frontiers in Genetics, 2020 Most species of Santalales (the sandalwood order) are hemiparasites, including both facultative and obligate hemiparasites. Despite its rich diversity, only a small fraction of the species in the sandalwood order have sequenced plastomes.
Xiaorong Guo +8 more
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Insects, 2023 Expanding on previous efforts to survey the visual opsin repertoires of the Hemiptera, this study confirms that homologs of the UV- and LW-opsin subfamilies are conserved in all Hemiptera, while the B-opsin subfamily is missing from the Heteroptera and ...
Markus Friedrich
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Gene Losses during Human Origins
PLoS Biology, 2006 Pseudogenization is a widespread phenomenon in genome evolution, and it has been proposed to serve as an engine of evolutionary change, especially during human origins (the "less-is-more" hypothesis). However, there has been no comprehensive analysis of human-specific pseudogenes.
Xiaoxia Wang +2 more
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Antivirulence Genes: Insights into Pathogen Evolution through Gene Loss [PDF]
Infection and Immunity, 2012 ABSTRACT The emergence of new pathogens and the exploitation of novel pathogenic niches by bacteria typically require the horizontal transfer of virulence factors and subsequent adaptation—a “fine-tuning” process—for the successful incorporation of these factors into the microbe's genome.
Kimberly A, Bliven, Anthony T, Maurelli
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Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition [PDF]
, 2016 Perforin, a pore-forming toxin released from secretory granules of NK cells and CTLs, is essential for their cytotoxic activity against infected or cancerous target cells.
Chaudhry, MS +7 more
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Phylogenetic reconstruction with gene rearrangements and gene losses [PDF]
2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2010 Reconstructing phylogenies from gene-order data has become very attractive in the research of evolution these years. So far, most methods can only treat genomes with equal gene contents with each gene appearing exactly once in each genome. In this paper, we propose a new distance measurement for genomes with inversions and insertions/deletions that ...
Yiwei Zhang, Fei Hu, Jijun Tang
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RB loss contributes to aggressive tumor phenotypes in MYC-driven triple negative breast cancer [PDF]
, 2015 Triple negative breast cancer (TNBC) is characterized by multiple genetic events occurring in concert to drive pathogenic features of the disease. Here we interrogated the coordinate impact of p53, RB, and MYC in a genetic model of TNBC, in parallel with
Ertel, Adam +5 more
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Evolutionary Histories of Type III Polyketide Synthases in Fungi
Frontiers in Microbiology, 2020 Type III polyketide synthases (PKSs) produce secondary metabolites with diverse biological activities, including antimicrobials. While they have been extensively studied in plants and bacteria, only a handful of type III PKSs from fungi has been ...
Jorge Carlos Navarro-Muñoz +1 more
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