Results 1 to 10 of about 7,142,405 (245)

The Gene Ontology knowledgebase in 2023. [PDF]

Genetics, 2023
The Gene Ontology (GO) knowledgebase (http://geneontology.org) is a comprehensive resource concerning the functions of genes and gene products (proteins and noncoding RNAs).
Gene Ontology Consortium, Aleksander SA, Balhoff J, Carbon S, Cherry JM, Drabkin HJ, Ebert D, Feuermann M, Gaudet P, Harris NL, Hill DP, Lee R, Mi H, Moxon S, Mungall CJ, Muruganugan A, Mushayahama T, Sternberg PW, Thomas PD, Van Auken K, Ramsey J, Siegele DA, Chisholm RL, Fey P, Aspromonte MC, Nugnes MV, Quaglia F, Tosatto S, Giglio M, Nadendla S, Antonazzo G, Attrill H, Dos Santos G, Marygold S, Strelets V, Tabone CJ, Thurmond J, Zhou P, Ahmed SH, Asanitthong P, Luna Buitrago D, Erdol MN, Gage MC, Ali Kadhum M, Li KYC, Long M, Michalak A, Pesala A, Pritazahra A, Saverimuttu SCC, Su R, Thurlow KE, Lovering RC, Logie C, Oliferenko S, Blake J, Christie K, Corbani L, Dolan ME, Drabkin HJ, Hill DP, Ni L, Sitnikov D, Smith C, Cuzick A, Seager J, Cooper L, Elser J, Jaiswal P, Gupta P, Jaiswal P, Naithani S, Lera-Ramirez M, Rutherford K, Wood V, De Pons JL, Dwinell MR, Hayman GT, Kaldunski ML, Kwitek AE, Laulederkind SJF, Tutaj MA, Vedi M, Wang SJ, D'Eustachio P, Aimo L, Axelsen K, Bridge A, Hyka-Nouspikel N, Morgat A, Aleksander SA, Cherry JM, Engel SR, Karra K, Miyasato SR, Nash RS, Skrzypek MS, Weng S, Wong ED, Bakker E, Berardini TZ, Reiser L, Auchincloss A, Axelsen K, Argoud-Puy G, Blatter MC, Boutet E, Breuza L, Bridge A, Casals-Casas C, Coudert E, Estreicher A, Livia Famiglietti M, Feuermann M, Gos A, Gruaz-Gumowski N, Hulo C, Hyka-Nouspikel N, Jungo F, Le Mercier P, Lieberherr D, Masson P, Morgat A, Pedruzzi I, Pourcel L, Poux S, Rivoire C, Sundaram S, Bateman A, Bowler-Barnett E, Bye-A-Jee H, Denny P, Ignatchenko A, Ishtiaq R, Lock A, Lussi Y, Magrane M, Martin MJ, Orchard S, Raposo P, Speretta E, Tyagi N, Warner K, Zaru R, Diehl AD, Lee R, Chan J, Diamantakis S, Raciti D, Zarowiecki M, Fisher M, James-Zorn C, Ponferrada V, Zorn A, Ramachandran S, Ruzicka L, Westerfield M.   +156 more
europepmc   +2 more sources

rrvgo: a Bioconductor package for interpreting lists of Gene Ontology terms. [PDF]

MicroPubl Biol, 2023
Gene Ontology (GO) annotation is often used to guide the biological interpretation of high-throughput omics experiments, e.g. by analysing lists of differentially regulated genes for enriched GO terms. Due to the hierarchical nature of GOs, the resulting
Sayols S.
europepmc   +2 more sources

Expansion of the Gene Ontology knowledgebase and resources [PDF]

Nucleic Acids Res., 2016
The Gene Ontology (GO) is a comprehensive resource of computable knowledge regarding the functions of genes and gene products. As such, it is extensively used by the biomedical research community for the analysis of -omics and related data. Our continued
Gene Ontology Consortium
semanticscholar   +3 more sources

GOLEM: an interactive graph-based gene-ontology navigation and analysis tool [PDF]

BMC Bioinformatics, 2006
Background The Gene Ontology has become an extremely useful tool for the analysis of genomic data and structuring of biological knowledge. Several excellent software tools for navigating the gene ontology have been developed.
Huttenhower Curtis, Hibbs Matthew A, Sealfon Rachel SG, Myers Chad L, Troyanskaya Olga G   +4 more
doaj   +2 more sources

The Gene Ontology Resource: 20 years and still GOing strong [PDF]

Nucleic Acids Res., 2018
The Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products.
Gene Ontology Consortium
semanticscholar   +6 more sources

CirGO: an alternative circular way of visualising gene ontology terms

BMC Bioinformatics, 2019
Background Prioritisation of gene ontology terms from differential gene expression analyses in a two-dimensional format remains a challenge with exponentially growing data volumes.
Irina Kuznetsova, Artur Lugmayr, Stefan J. Siira, Oliver Rackham, Aleksandra Filipovska   +4 more
doaj   +2 more sources

Capturing heart valve development with Gene Ontology [PDF]

Frontiers in Genetics, 2023
Introduction: The normal development of all heart valves requires highly coordinated signaling pathways and downstream mediators. While genomic variants can be responsible for congenital valve disease, environmental factors can also play a role. Later in
Saadullah H. Ahmed, Alexander T. Deng, Rachael P. Huntley, Nancy H. Campbell, Ruth C. Lovering   +4 more
doaj   +2 more sources

Gene Ontology Meta Annotator for Plants (GOMAP)

Plant Methods, 2021
Annotating gene structures and functions to genome assemblies is necessary to make assembly resources useful for biological inference. Gene Ontology (GO) term assignment is the most used functional annotation system, and new methods for GO assignment ...
Kokulapalan Wimalanathan, Carolyn J. Lawrence-Dill   +1 more
doaj   +2 more sources

Defining functional distances over Gene Ontology [PDF]

BMC Bioinformatics, 2008
Background A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-structured ontologies exist regarding the activity of proteins (i.e.
del Pozo Angela, Pazos Florencio, Valencia Alfonso   +2 more
doaj   +2 more sources

Combining gene ontology with deep neural networks to enhance the clustering of single cell RNA-Seq data

BMC Bioinformatics, 2019
Background Single cell RNA sequencing (scRNA-seq) is applied to assay the individual transcriptomes of large numbers of cells. The gene expression at single-cell level provides an opportunity for better understanding of cell function and new discoveries ...
Jiajie Peng, Xiaoyu Wang, Xuequn Shang
doaj   +2 more sources