Gene Ontology Consortium: going forward [PDF]
Nucleic Acids Research, 2015 The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge.
Gene Ontology Consortium
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GOLEM: an interactive graph-based gene-ontology navigation and analysis tool [PDF]
BMC Bioinformatics, 2006 Background The Gene Ontology has become an extremely useful tool for the analysis of genomic data and structuring of biological knowledge. Several excellent software tools for navigating the gene ontology have been developed.
Huttenhower Curtis +4 more
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Capturing heart valve development with Gene Ontology [PDF]
Frontiers in Genetics, 2023 Introduction: The normal development of all heart valves requires highly coordinated signaling pathways and downstream mediators. While genomic variants can be responsible for congenital valve disease, environmental factors can also play a role. Later in
Saadullah H. Ahmed +4 more
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Comparative GO: a web application for comparative gene ontology and gene ontology-based gene selection in bacteria. [PDF]
PLoS ONE, 2013 The primary means of classifying new functions for genes and proteins relies on Gene Ontology (GO), which defines genes/proteins using a controlled vocabulary in terms of their Molecular Function, Biological Process and Cellular Component.
Mario Fruzangohar +5 more
doaj +7 more sources
The Devices, Experimental Scaffolds, and Biomaterials Ontology (DEB): A Tool for Mapping, Annotation, and Analysis of Biomaterials Data [PDF]
Advanced Functional Materials, 2020 The size and complexity of the biomaterials literature makes systematic data analysis an excruciating manual task. A practical solution is creating databases and information resources.
Osnat Hakimi +2 more
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Defining functional distances over Gene Ontology [PDF]
BMC Bioinformatics, 2008 Background A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-structured ontologies exist regarding the activity of proteins (i.e.
del Pozo Angela +2 more
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Frontiers in Psychology, 2017 Handedness and language lateralization are partially determined by genetic influences. It has been estimated that at least 40 (and potentially more) possibly interacting genes may influence the ontogenesis of hemispheric asymmetries.
Judith Schmitz +2 more
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The Gene Ontology resource: enriching a GOld mine. [PDF]
, 2021 The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium over the past two years.
Gene Ontology Consortium
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The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species. [PDF]
PLoS Computational Biology, 2009 The Gene Ontology (GO) is a collaborative effort that provides structured vocabularies for annotating the molecular function, biological role, and cellular location of gene products in a highly systematic way and in a species-neutral manner with the aim ...
Reference Genome Group of the Gene Ontology Consortium
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On the Use of Gene Ontology Annotations to Assess Functional Similarity among Orthologs and Paralogs: A Short Report. [PDF]
PLoS Computational Biology, 2012 A recent paper (Nehrt et al., PLoS Comput. Biol. 7:e1002073, 2011) has proposed a metric for the "functional similarity" between two genes that uses only the Gene Ontology (GO) annotations directly derived from published experimental results.
Paul D Thomas +5 more
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