Results 101 to 110 of about 159,072 (309)

IGH gene rearrangement in Acute Lymphoid Leukemia: A study from western region of India

, 2022
Acute lymphoblastic Leukemia (ALL) is found to be a heterogeneous disorder that coexists with multiple clones. The treatment and outcome of ALL is dependent on risk stratifications of ALL patients that is decided on the basis of prognostic factors such ...
K. Varma, Priya, M. Patel, Dharmesh, Patel, Archana, Trivedi, Pina J., M. Kazi, Mahnaz   +4 more
core  

3D Printing Innovations in Polymeric Porous and Patterned Architecture

Advanced Functional Materials, EarlyView.
Polymeric foams occupy a unique structural space between dense solids and open networks, where engineered void fraction governs mechanical compliance, thermal resistance, and mass transport. Additive manufacturing now enables precise spatial control over cellular architecture, unlocking designer foam structures across applications spanning crash ...
Dhanush Patil, Sri Vaishnavi Thummalapalli, Clarissa Westover, Arunachalam Ramanathan, M. Taylor Sobzcak, Roumika Patil, Qixuan Xiang, Tiantian Li, Sui Yang, Timothy E. Long, Hongyue Sun, Xianqiao Wang, Yang Liu, Kenan Song   +13 more
wiley   +1 more source

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling [PDF]

, 2005
To gain more insight into initiation and regulation of T cell receptor (TCR) gene rearrangement during human T cell development, we analyzed TCR gene rearrangements by quantitative PCR analysis in nine consecutive T cell ...
Edwin F.E. de Haas, Floor Weerkamp, Dongen, J.J.M. (Jacques) van, Langerak, A.W. (Anton), Weerkamp, F. (Floor), Esther E.L. Koster, Baert, M.R.M. (Miranda), Spek, P.J. (Peter) van der, Dick de Ridder, Koster, E.E. (Esther), Peter van der Spek, Jacques J.M. van Dongen, Anton W. Langerak, Ridder, D. (Dick) de, Pike, K. (Karin), Haas, E.F. (Edwin) de, Marcel J.T. Reinders, Frank J.T. Staal, Miranda R.M. Baert, Karin Pike-Overzet, Reinders, M.J. (Marcel), Willem A. Dik, Staal, F.J.T. (Frank), Dik, W.A. (Willem)   +23 more
core   +1 more source

Immunoglobulin lambda gene rearrangement can precede kappa gene rearrangement.

Developmental immunology, 1992
Immunoglobulin genes are generated during differentiation of B lymphocytes by joining gene segments. A mouse pre-B cell contains a functional immunoglobulin heavy-chain gene, but no light-chain gene. Although there is only one heavy-chain locus, there are two light-chain loci: kappa and lambda.
J, Berg, M, McDowell, H M, Jäck, M, Wabl   +3 more
openaire   +1 more source

Application of Ibuprofen Sodium Dihydrate for Thermochemical Energy Storage

Advanced Functional Materials, EarlyView.
Ibuprofen sodium dihydrate is introduced as a durable organic salt hydrate for low‐temperature thermochemical energy storage, operating within 60°C–110°C with high energy density. At the material level, it delivers ∼99.9% cycling efficiency over 150 cycles without deliquescence, enabled by a dual energy‐storage mechanism coupling dehydration and phase ...
Kavin Chakravarthy Thangaraj, Hannah F. Chang, Shannon J. Lee, Mark E. Bowden, J. David Bazak, Vaithiyalingam Shutthanandan, Venkateshkumar Prabhakaran, Xiao Zhang, David M. Reed, Ajay S. Karakoti, Vijayakumar Murugesan   +10 more
wiley   +1 more source

Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms

, 2009
Baumbach J, Rahmann S, Tauch A. Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms. BMC Systems Biology.
Sven Rahmann, Andreas Tauch, Tauch, Andreas, Baumbach, Jan, Jan Baumbach, Rahmann, Sven   +5 more
core   +1 more source

Antibody-Based Detection of ERG Rearrangement-Positive Prostate Cancer

Neoplasia: An International Journal for Oncology Research, 2010
TMPRSS2-ERG gene fusions occur in 50% of prostate cancers and result in the overexpression of a chimeric fusion transcript that encodes a truncated ERG product.
Kyung Park, Scott A. Tomlins, Kumaran M. Mudaliar, Ya-Lin Chiu, Raquel Esgueva, Rohit Mehra, Khalid Suleman, Sooryanarayana Varambally, John C. Brenner, Theresa MacDonald, Abhishek Srivastava, Ashutosh K. Tewari, Ubaradka Sathyanarayana, Dea Nagy, Gary Pestano, Lakshmi P. Kunju, Francesca Demichelis, Arul M. Chinnaiyan, Mark A. Rubin   +18 more
doaj   +1 more source

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

Advanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach, Reza Kowsari‐Esfahan, Emilia Reszczyńska, Philippe Nghe, Matthias Nees   +4 more
wiley   +1 more source

Analysis of the Leukemogenic Potential of the CALM/AF10 Fusion Gene in Patients, Transgenic Mice and Cell Culture Models

, 2006
The t(10;11)(p13;q14) is a recurring translocation resulting in the fusion of the CALM and AF10 genes. The leukemogenic CALM/AF10 fusion genes codes for a 1595 amino acids protein.
Krause, Alexandre
core  

Rampant gene rearrangement and haplotype hypervariation among nematode mitochondrial genomes [PDF]

, 2010
Rare syntenic conservation, sequence duplication, and the use of both DNA strands to encode genes are signature architectural features defining mitochondrial genomes of enoplean nematodes.
Sha Tang, Tang, Sha, Bradley C. Hyman, Samantha C. Lewis, Wu, Zhen, Hyman, Bradley C, Zhen Wu, Lewis, Samantha C   +7 more
core   +1 more source