Results 31 to 40 of about 6,798,395 (302)
Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements [PDF]
PNAS vol 100, p 7853 (2003), 2005 The ALL-1 gene is directly involved in 5-10% of ALLs and AMLs by fusion to other genes or through internal rearrangements. DNA microarrays were utilized to determine expression profiles of ALLs and AMLs with ALL-1 rearrangements. These profiles distinguish those tumors from other ALLs and AMLs.
arxiv +1 more source
Genome rearrangement with gene families [PDF]
Bioinformatics, 1999 Abstract Motivation: The theory and practice of genome rearrangement analysis breaks down in the biologically widespread contexts where each gene may be present in a number of copies, not necessarily contiguous. In some of these contexts it is, however, appropriate to ask which members of each gene family in two genomes G and H, lengths ...
openaire +3 more sources
Pre-B-cell acute lymphoblastic leukemia with bulk extramedullary disease and chromosome 22 (EWSR1) rearrangement masquerading as Ewing sarcoma [PDF]
, 2010 We report a 2-year-old female with a subcutaneous tumor who was initially misdiagnosed as suffering from Ewing sarcoma with a positive EWSR1 rearrangement and EWS/FLI1 transcript.
Jakovljević, Gordana +6 more
core +1 more source
Antigen receptor sequencing of paired bone marrow samples shows homogeneous distribution of acute lymphoblastic leukemia subclones [PDF]
, 2017 In B-cell precursor acute lymphoblastic leukemia, the initial leukemic cells share the same antigen receptor gene rearrangements. However, due to ongoing rearrangement processes, leukemic cells with different gene rearrangement patterns can develop ...
Dongen, J.J.M. (Jacques) van +6 more
core +3 more sources
Immunoglobulin λ Gene Rearrangement Can Precede κ Gene Rearrangement [PDF]
Journal of Immunology Research, 1989 Immunoglobulin genes are generated during differentiation of B lymphocytes by joining gene segments. A mouse pre‐B cell contains a functional immunoglobulin heavy‐chain gene, but no light‐chain gene. Although there is only one heavy‐chain locus, there are two lightchain loci: κ and λ.It has been reported that κ loci in the germ‐line configuration are ...
Jörg Berg +3 more
openaire +2 more sources
Three New Ranidae Mitogenomes and the Evolution of Mitochondrial Gene Rearrangements among Ranidae Species [PDF]
, 2018 Various types of gene rearrangements have been discovered in the mitogenoes of the frog family Ranidae. In this study, we determined the complete mitogenome sequence of three Rana frogs.
Biao LI +5 more
core +1 more source
A Case of Rearrangement of Genes in Drosophila [PDF]
Proceedings of the National Academy of Sciences, 1921 Seven mutant genes of Drosophila simulans have been shown to be allelomorphic to previously known mutant genes of D. melanogaster. Five of these lie in the X-chromosome, and a study of their linkage relations was shown to indicate that the sequence of the five loci concerned is the same in both species, and that the percentages of crossing over in ...
openaire +5 more sources
Thoracic Cancer, 2019 Background The study was conducted to evaluate the clinical and computed tomography (CT) findings of non‐small cell lung cancer (NSCLC) patients to distinguish between ALK gene rearrangement, EGFR mutation, and non‐ALK/EGFR (no genetic abnormalities ...
Mio Mori +12 more
doaj +1 more source
Egyptian Journal of Chest Disease and Tuberculosis, 2018 Patients and methods Testing for Anaplastic Lymphoma Kinas (ALK) rearrangement is now recommended for selection of lung cancer patients targeted for Tyrosine-kinase inhibitors (Crizotimib).
Mohamed Hantera +4 more
doaj +1 more source
T-gamma gene rearrangement and CMV mononucleosis [PDF]
American Journal of Hematology, 2000 A clonal T-gamma rearrangement was found in peripheral blood and bone marrow in a 57-year-old female who presented with 6-week history of fevers, night sweats, and weight loss. Splenomegaly, hemolytic anemia, atypical lymphocytosis, a marrow lymphoid aggregate, and elevated LDH had suggested lymphoproliferative disease.
Deborah A. Payne +3 more
openaire +3 more sources