Results 41 to 50 of about 260,281 (335)

T cell factor-1 controls the lifetime of CD4+ CD8+ thymocytes in vivo and distal T cell receptor α-chain rearrangement required for NKT cell development. [PDF]

PLoS ONE, 2014
Natural killer T (NKT) cells are a component of innate and adaptive immune systems implicated in immune, autoimmune responses and in the control of obesity and cancer.
Archna Sharma, Rosa Berga-Bolaños, Jyoti Misra Sen   +2 more
doaj   +1 more source

A new transcript in the TCRB locus unveils the human ortholog of the mouse pre-Dß1 promoter [PDF]

, 2017
Introduction: While most transcripts arising from the human T Cell Receptor locus reflect fully rearranged genes, several germline transcripts have been identified. We describe a new germline transcript arising from the human TCRB locus.
Abarrategui, Berman, Bustin, Calman, Cobb, Davodeau, de Villartay, Dik, Dombret, Doty, Duber, Engel, Gottschalk, Joachims, Khor, Lennon, Lurquin, Mathieu, Matz, Osipovich, Padovan, Pelicci, Ramiro, Schlissel, Schweingruber, Senapathy, Sikes, Sikes, Spicuglia, Szczepanski, Taghon, Thomas, Whitehurst, Yancopoulos   +33 more
core   +2 more sources

The highly rearranged mitochondrial genomes of the crabs Maja crispata and Maja squinado (Majidae) and gene order evolution in Brachyura [PDF]

, 2017
We sequenced the mitochondrial genomes of the spider crabs Maja crispata and Maja squinado (Majidae, Brachyura). Both genomes contain the whole set of 37 genes characteristic of Bilaterian genomes, encoded on both \u3b1- and \u3b2-strands.
AD Miller, AE Smith, AH Sahyoun, AT Beckenbach, BQ Minh, C Hahn, C Moritz, DR Wolstenholme, DV Lavrov, E Negrisolo, F Jühling, F Kilpert, FJ Lin, G Shi, G Shi, G Sotelo, G Tan, G Tang, H Ma, H Shen, H Shimodaira, H Sun, I Marcadé, IM Fearnley, J Yang, JD Thompson, JL Boore, JL Boore, JL Boore, JL Boore, JM Sung, JM Sung, JS Ki, K Strimmer, K Tamura, LM Tsang, LS Quang, LT Nguyen, M Babbucci, M Bernt, M Bernt, M Bernt, M Dowton, M Hui, MH Tan, MH Tan, MM Yamauchi, N Lartillot, NT Perna, O Rota-Stabelli, P Cantatore, P Salvato, R Lanfear, R Raimond, RD Segawa, S Grave De, S Montelli, S Saito, SF Altschul, SJ Kim, SL Cameron, TA Rawlings, TM Lowe, X Wang, Y Xing, YK Ji, YQ Yu, Z Yang   +67 more
core   +1 more source

Hidden breakpoints in genome alignments

, 2012
During the course of evolution, an organism's genome can undergo changes that affect the large-scale structure of the genome. These changes include gene gain, loss, duplication, chromosome fusion, fission, and rearrangement.
A. Rambaut, A.C.E. Darling, A.E. Darling, A.L. Delcher, C.D. Greenman, D. Medini, E. Tannier, G. Fudenberg, M. Blanchette, M. Nowacki, M.A. Umbarger, S. De, S. Schwartz, S.V. Angiuoli, V. Kolmogorov   +14 more
core   +1 more source

Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia [PDF]

, 2012
TO THE EDITOR: We read an interesting paper by Palta et al. in a recent issue of the Korean Journal of Hematology titled, "ZBTB16-RARA variant of acute promyelocytic leukemia with tuberculosis: a case report and review of literature" [1].
Kim, Min Jin, Marschalek, Rolf, Meyer, Claus, Park, Tae Sung, Yang, John Jeongseok   +4 more
core   +1 more source

NR4A3 (NOR-1) Immunostaining Shows Better Performance than DOG1 Immunostaining in Acinic Cell Carcinoma of Salivary Gland: a Preliminary Study

eJournal of Oral Maxillofacial Research, 2021
Objectives: Acinic cell carcinoma of salivary gland harbours recurrent and specific chromosomal rearrangement [t(4;9)(q13;q31)], resulting in the translocation of secretory calcium-binding phosphoprotein gene cluster at 4q13 to nuclear receptor subfamily
Adepitan Owosho, Donald Tyler, Olufunlola Adesina, Oluwole Odujoko, Kurt Summersgill   +4 more
doaj   +1 more source

Programmed Gene Rearrangements Altering Gene Expression

Science, 1987
Programmed gene rearrangements are used in nature to alter gene copy number (gene amplification and deletion), to create diversity by reassorting gene segments (as in the formation of mammalian immunoglobulin genes), or to control the expression of a set of genes that code for the same function (such as surface antigens).
Borst, P, Greaves, D
openaire   +4 more sources

Impact of observational incompleteness on the structural properties of protein interaction networks

, 2006
The observed structure of protein interaction networks is corrupted by many false positive/negative links. This observational incompleteness is abstracted as random link removal and a specific, experimentally motivated (spoke) link rearrangement.
Albert, Alfarano, Bader, Bader, Berg, Breitkreutz, Dall’Asta, Deane, Eisenberg, Gavin, Ho, Ingmar Glauche, Ispolatov, Ispolatov, Lee, Martin Greiner, Mathias Kuhnt, Mering, Milo, Newman, Przulj, Salwinski, Scholz, Sole, Tong, Vazquez, Vazquez, Zanzoni, Ziv   +28 more
core   +1 more source

scTCR-seq and HTS reveal a special novel TRBD2-TRBJ1 rearrangement in mammalian TRB CDR3 repertoire

BMC Genomics
Mammalian T cell receptor (TCR) beta-chain (TRB) V-D-J rearrangement mainly follows the “12/23 rule”, and the “D-J rearrangement preceding the V-(D-J) rearrangement”.
Yingjie Wu, Fengli Wu, Jun Li, Hao Zhou, Long Ma, Xinsheng Yao   +5 more
doaj   +1 more source

Anaplastic lymphoma kinase-positive pulmonary inflammatory myofibroblastic tumor with sarcomatous morphology and distant metastases: An unusual histomorphology and behavior

Indian Journal of Pathology and Microbiology, 2015
Inflammatory myofibroblastic tumor (IMT), an intermediate-grade neoplasm of myofibroblastic/fibroblastic differentiation, occurs commonly in children and young adults.
Bhawna Sethi, Trupti Pai, Abhishek Allam, Sridhar Epari   +3 more
doaj   +1 more source