Results 41 to 50 of about 271,468 (359)

Impact of observational incompleteness on the structural properties of protein interaction networks

, 2006
The observed structure of protein interaction networks is corrupted by many false positive/negative links. This observational incompleteness is abstracted as random link removal and a specific, experimentally motivated (spoke) link rearrangement.
Albert, Alfarano, Bader, Bader, Berg, Breitkreutz, Dall’Asta, Deane, Eisenberg, Gavin, Ho, Ingmar Glauche, Ispolatov, Ispolatov, Lee, Martin Greiner, Mathias Kuhnt, Mering, Milo, Newman, Przulj, Salwinski, Scholz, Sole, Tong, Vazquez, Vazquez, Zanzoni, Ziv   +28 more
core   +1 more source

The zero exemplar distance problem [PDF]

, 2010
Given two genomes with duplicate genes, \textsc{Zero Exemplar Distance} is the problem of deciding whether the two genomes can be reduced to the same genome without duplicate genes by deleting all but one copy of each gene in each genome.
D. Sankoff, G. Blin, J.E. Hopcroft, M.R. Garey, P. Bonizzoni, R.G. Downey, S. Angibaud, S.S. Adi, V. Ferretti, Z. Chen, Z. Chen   +10 more
core   +1 more source

Gene content evolution in the arthropods [PDF]

, 2020
Arthropods comprise the largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem. Their diversity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes in the genome ...
Anstead, Clare A., Ayoub, Nadia A., Batterham, Phillip, Bellair, Michelle, Benoit, Joshua B., Binford, Greta J., Bornberg-Bauer, Erich, Chao, Hsu, Chen, Yolanda H., Childers, Christopher, Chipman, Ariel D., Dinh, Huyen, Doddapaneni, Harsha Vardhan, Dohmen, Elias, Duan, Jian J., Dugan, Shannon, Esposito, Lauren A., Friedrich, Markus, Garb, Jessica, Gasser, Robin B., Gibbs, Richard A., Glastad, Karl, Goodisman, Michael A. D., Gundersen-Rindal, Dawn E., Hackett, Kevin J., Hahn, Matthew W., Han, Yi, Handler, Alfred M., Hatakeyama, Masatsugu, Hering, Lars, Hughes, Daniel S. T., Hunter, Wayne B., Ioannidis, Panagiotis, Jayaseelan, Joy C., Kalra, Divya, Khila, Abderrahman, Korhonen, Pasi K, Lee, Carol Eunmi, Lee, Sandra L., Li, Yiyuan, Lindsey, Amelia R. I., Mayer, Georg, McGregor, Alistair P., McKenna, Duane D., Misof, Bernhard, Munidasa, Mala, Munoz-Torres, Monica, Murali, Shwetha C., Muzny, Donna M., Niehuis, Oliver, Osuji-Lacy, Nkechinyere, Palli, Subba R., Panfilio, Kristen A., Pechmann, Matthias, Perry, Trent, Peters, Ralph S., Pfrender, Michael E., Poelchau, Monica, Poynton, Helen C., Prpic, Nikola-Michael, Qu, Jiaxin, Richards, Stephen, Rotenberg, Dorith, Schal, Coby, Schoville, Sean D., Scully, Erin D., Skinner, Evette, Sloan, Daniel B., Stouthamer, Richard, Strand, Michael R., Szucsich, Nikolaus U., Thomas, Gregg W. C., Waterhouse, Robert M., Werren, John H., Wijeratne, Asela, Worley, Kim C., Young, Neil D., Zattara, Eduardo E., Zdobnov, Evgeny M.   +78 more
core   +5 more sources

scTCR-seq and HTS reveal a special novel TRBD2-TRBJ1 rearrangement in mammalian TRB CDR3 repertoire

BMC Genomics
Mammalian T cell receptor (TCR) beta-chain (TRB) V-D-J rearrangement mainly follows the “12/23 rule”, and the “D-J rearrangement preceding the V-(D-J) rearrangement”.
Yingjie Wu, Fengli Wu, Jun Li, Hao Zhou, Long Ma, Xinsheng Yao   +5 more
doaj   +1 more source

Marfan syndrome with a complex chromosomal rearrangement including deletion of the FBN1 gene

Molecular Cytogenetics, 2012
Background The majority of Marfan syndrome (MFS) cases is caused by mutations in the fibrillin-1 gene (FBN1), mapped to chromosome 15q21.1. Only few reports on deletions including the whole FBN1 gene, detected by molecular cytogenetic techniques, were ...
Colovati Mileny ES, da Silva Luciana RJ, Takeno Sylvia S, Mancini Tatiane I, N Dutra Ana R, Guilherme Roberta S, de Mello Cláudia B, Melaragno Maria I, A Perez Ana B   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Anaplastic lymphoma kinase-positive pulmonary inflammatory myofibroblastic tumor with sarcomatous morphology and distant metastases: An unusual histomorphology and behavior

Indian Journal of Pathology and Microbiology, 2015
Inflammatory myofibroblastic tumor (IMT), an intermediate-grade neoplasm of myofibroblastic/fibroblastic differentiation, occurs commonly in children and young adults.
Bhawna Sethi, Trupti Pai, Abhishek Allam, Sridhar Epari   +3 more
doaj   +1 more source

Comparative Analysis of Complete Mitochondrial Genome of Ariosoma meeki (Jordan and Snider, 1900), Revealing Gene Rearrangement and the Phylogenetic Relationships of Anguilliformes

Biology, 2023
The mitochondrial genome structure of a teleostean group is generally considered to be conservative. However, two types of gene arrangements have been identified in the mitogenomes of Anguilliformes.
Youkun Huang, Kehua Zhu, Yawei Yang, Liancheng Fang, Zhaowen Liu, Jia Ye, Caiyi Jia, Jianbin Chen, Hui Jiang   +8 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Is now the time for molecular driven therapy for diffuse large B-cell lymphoma? [PDF]

, 2017
INTRODUCTION: Recent genetic and molecular discoveries regarding alterations in diffuse large B-cell lymphoma (DLBCL) deeply changed the approach to this lymphoproliferative disorder.
Ansuinelli, Michela, DE ANGELIS, Federico, DI ROCCO, Alice, Foa, Roberto, Martelli, Maurizio   +4 more
core   +1 more source