Results 41 to 50 of about 6,798,395 (302)

A new transcript in the TCRB locus unveils the human ortholog of the mouse pre-Dß1 promoter [PDF]

, 2017
Introduction: While most transcripts arising from the human T Cell Receptor locus reflect fully rearranged genes, several germline transcripts have been identified. We describe a new germline transcript arising from the human TCRB locus.
Abarrategui, Berman, Bustin, Calman, Cobb, Davodeau, de Villartay, Dik, Dombret, Doty, Duber, Engel, Gottschalk, Joachims, Khor, Lennon, Lurquin, Mathieu, Matz, Osipovich, Padovan, Pelicci, Ramiro, Schlissel, Schweingruber, Senapathy, Sikes, Sikes, Spicuglia, Szczepanski, Taghon, Thomas, Whitehurst, Yancopoulos   +33 more
core   +2 more sources

Epithelioid and spindle rhabdomyosarcoma with TFCP2 rearrangement in abdominal wall: a distinctive entity with poor prognosis

Diagnostic Pathology, 2023
Background Epithelioid and spindle rhabdomyosarcoma (ES-RMS) with TFCP2 rearrangement is a recently discovered rare variant of rhabdomyosarcoma composed of epithelioid and spindle cells, because it shows extraordinarily adverse prognosis and is easily ...
Yuan Li, Dan Li, Jingyu Wang, Jinlong Tang   +3 more
doaj   +1 more source

A novel three-colour fluorescence in situ hybridization approach for the detection of t(7;12)(q36;p13) in acute myeloid leukaemia reveals new cryptic three way translocation t(7;12;16) [PDF]

, 2013
© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).The t(7;12)(q36;p13 ...
Abdulbasit Naiel, Andreasson, Beverloo, Cho, Elena Fleischman, Grigory Tsaur, Hollington, Jochen Harbott, Michael Vetter, Olga Plekhanova, Olga Sokova, Raimondi, Sabrina Tosi, Wildenhain, Wlodarska   +14 more
core   +2 more sources

Correlations between BCL6 rearrangement and outcome in patients with diffuse large B-cell lymphoma treated with CHOP or R-CHOP

Haematologica, 2010
Background BCL6 gene rearrangement is the most frequent chromosomal abnormality in diffuse large B-cell lymphoma, a malignancy characterized by genetic heterogeneity and wide variability in clinical outcome.
Jesse Shustik, Guangming Han, Pedro Farinha, Nathalie A. Johnson, Susana Ben Neriah, Joseph M. Connors, Laurie H. Sehn, Douglas E. Horsman, Randy D. Gascoyne, Christian Steidl   +9 more
doaj   +1 more source

The clinical characteristics of autoimmune haemolytic anaemia/Evans syndrome patients with clonal immunoglobulin/T cell receptor gene rearrangement

Autoimmunity, 2020
Objective To investigate the clinical features of AIHA/ES patients with clonal Ig/TCR gene rearrangement. Methods Ig/TCR gene rearrangements were measured by BIOMED-2 PCR. 44 primary AIHA/ES patients were enrolled in the study.
Hongli Zhu, Manjun Zhao, Zeng Cao, Jin Yang, Yi Li, Limin Xing   +5 more
doaj   +1 more source

Molecular testing for the clinical diagnosis of fibrolamellar carcinoma. [PDF]

, 2018
Fibrolamellar carcinoma has a distinctive morphology and immunophenotype, including cytokeratin 7 and CD68 co-expression. Despite the distinct findings, accurate diagnosis of fibrolamellar carcinoma continues to be a challenge.
Alves, Venancio Af, Cruise, Michael W, Ferrell, Linda, Gill, Ryan M, Graham, Rondell P, Greipp, Patricia T, Jain, Dhanpat, Jin, Long, Kakar, Sanjay, Kerr, Sarah E, Lam-Himlin, Dora, Longerich, Thomas, Nart, Deniz, Roberts, Lewis R, Roessler, Stephanie, Rustin, Jeanette G, Salaria, Safia N, Schirmacher, Peter, Solomon, David A, Sukov, William R, Terracciano, Luigi, Torbenson, Michael S, Wang, Xiaoke, Waterhouse, Emily, Yeh, Matthew M, Yilmaz, Funda, Zaid, Nida, Zreik, Riyam T   +27 more
core   +1 more source

Comparative genomic analysis of vertebrate mitochondrial reveals a differential of rearrangements rate between taxonomic class

Scientific Reports, 2022
Vertebrate mitochondrial genomes have been extensively studied for genetic and evolutionary purposes, these are normally believed to be extremely conserved, however, different cases of gene rearrangements have been reported.
Paula Montaña-Lozano, Manuela Moreno-Carmona, Mauricio Ochoa-Capera, Natalia S. Medina, Jeffrey L. Boore, Carlos F. Prada   +5 more
doaj   +1 more source

The highly rearranged mitochondrial genomes of the crabs Maja crispata and Maja squinado (Majidae) and gene order evolution in Brachyura [PDF]

, 2017
We sequenced the mitochondrial genomes of the spider crabs Maja crispata and Maja squinado (Majidae, Brachyura). Both genomes contain the whole set of 37 genes characteristic of Bilaterian genomes, encoded on both \u3b1- and \u3b2-strands.
AD Miller, AE Smith, AH Sahyoun, AT Beckenbach, BQ Minh, C Hahn, C Moritz, DR Wolstenholme, DV Lavrov, E Negrisolo, F Jühling, F Kilpert, FJ Lin, G Shi, G Shi, G Sotelo, G Tan, G Tang, H Ma, H Shen, H Shimodaira, H Sun, I Marcadé, IM Fearnley, J Yang, JD Thompson, JL Boore, JL Boore, JL Boore, JL Boore, JM Sung, JM Sung, JS Ki, K Strimmer, K Tamura, LM Tsang, LS Quang, LT Nguyen, M Babbucci, M Bernt, M Bernt, M Bernt, M Dowton, M Hui, MH Tan, MH Tan, MM Yamauchi, N Lartillot, NT Perna, O Rota-Stabelli, P Cantatore, P Salvato, R Lanfear, R Raimond, RD Segawa, S Grave De, S Montelli, S Saito, SF Altschul, SJ Kim, SL Cameron, TA Rawlings, TM Lowe, X Wang, Y Xing, YK Ji, YQ Yu, Z Yang   +67 more
core   +1 more source

Detection of t(7;12)(q36;p13) in paediatric leukaemia using dual colour fluorescence in situ hybridisation [PDF]

, 2015
The identification of chromosomal rearrangements is of utmost importance for the diagnosis and classification of specific leukaemia subtypes and therefore has an impact on therapy choices in individual cases.
Federico, C, Owoka, T, Saccone, S, Tosi, S, Vetter, M   +4 more
core   +2 more sources

NKX3.1 Suppresses TMPRSS2-ERG Gene Rearrangement and Mediates Repair of Androgen Receptor-Induced DNA Damage.

Cancer Research, 2015
TMPRSS2 gene rearrangements occur at DNA breaks formed during androgen receptor-mediated transcription and activate expression of ETS transcription factors at the early stages of more than half of prostate cancers.
C. Bowen, T. Zheng, E. Gelmann
semanticscholar   +1 more source