Results 81 to 90 of about 6,798,395 (302)
On a break with the X: the role of repair of double-stranded DNA breaks in X-linked disease [PDF]
, 2012 The problem of managing free reactive DNA ends in eukaryotic cells has resulted in the development of a number of mechanisms in order to ensure that free ends are rendered non-reactive, or that the double-strand DNA breaks generating the free ends are ...
Cecceroni, Lucia +2 more
core +3 more sources
Sequencing and characterisation of rearrangements in three S. pastorianus strains reveals the presence of chimeric genes and gives evidence of breakpoint reuse [PDF]
, 2013 Gross chromosomal rearrangements have the potential to be evolutionarily advantageous to an adapting organism. The generation of a hybrid species increases opportunity for recombination by bringing together two homologous genomes. We sought to define the location of genomic rearrangements in three strains of Saccharomyces pastorianus, a natural lager ...
arxiv +1 more source
Statistical inference of the generation probability of T-cell receptors from sequence repertoires [PDF]
PNAS October 2, 2012 vol. 109 no. 40 16161-16166, 2012 Stochastic rearrangement of germline DNA by VDJ recombination is at the origin of immune system diversity. This process is implemented via a series of stochastic molecular events involving gene choices and random nucleotide insertions between, and deletions from, genes.
arxiv +1 more source
BMC Genomics, 2013 BackgroundMitochondrial genomic (mitogenomic) reorganizations are rarely found in closely-related animals, yet drastic reorganizations have been found in the Ranoides frogs.
A. Kurabayashi, M. Sumida
semanticscholar +1 more source
Scientific Reports, 2018 Animal mitochondrial genomes usually exhibit conserved gene arrangement across major lineages, while those in the Hymenoptera are known to possess frequent rearrangements, as are those of several other orders of insects.
Long Chen +6 more
doaj +1 more source
Open Biology, 2023 ATP-binding cassette subfamily B (ABCB) has been implicated in various essential functions such as multidrug resistance, auxin transport and heavy metal tolerance in animals and plants.
Xue Zhang +8 more
doaj +1 more source
Annals of Oncology, 2012 BACKGROUND A subgroup of anaplastic lymphoma kinase (ALK)-rearranged lung tumours can respond to ALK inhibitors. Until now, the ALK status in circulating tumour cells (CTCs) isolated from patients with lung cancer has not been characterised.
M. Ilié +13 more
semanticscholar +1 more source
Immunohistochemical and Molecular Characterization of Endometrial Stromal Sarcomas
Clinical Pathology, 2020 Introduction: Endometrial stromal sarcomas (ESSs) are rare and characterized by translocations t(7;17)(p15;q11.2) and t(10;17)(q22;p13), resulting in JAZF1-SUZ12 and YWHAE-FAM22 gene fusions used for defining low-grade (LG-ESS) and high-grade (HG-ESS ...
Sneha Subbaraya +2 more
doaj +1 more source
The mitogenome of the scale insect Didesmococcus koreanus Borchsenius, 1955 (Coccoidea: Coccidae)
Mitochondrial DNA. Part B. Resources, 2021 The complete mitochondrial genome of Didesmococcus koreanus is described in this study. The complete mitogenome is a 15,162 bp circular DNA molecule with a high A + T content of 82.5%, containing the typical 37 genes.
Han Xu, Xiaochen Liu, Hu Li, Sanan Wu
doaj +1 more source
A novel element upstream of the Vgamma2 gene in the murine T cell receptor gamma locus cooperates with the 3 enhancer to act as a locus control region. [PDF]
, 1999 Transgenic expression constructs were employed to identify a cis-acting transcription element in the T cell receptor (TCR)-gamma locus, called HsA, between the Vgamma5 and Vgamma2 genes. In constructs lacking the previously defined enhancer (3E(Cgamma1)),
Baker, J +5 more
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