Results 201 to 210 of about 2,989,814 (357)
Cocaine-induced gene regulation in D1 and D2 neuronal ensembles of the nucleus accumbens. [PDF]
Mews P+4 more
europepmc +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Coordinate regulation of transforming growth factor beta gene expression and cell proliferation in hamster lungs undergoing bleomycin-induced pulmonary fibrosis. [PDF]
B Raghow, Pati S. Irish, A H Kang
openalex +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Decoding microRNA arm switching: a key to evolutionary innovation and gene regulation. [PDF]
Pinhal D+3 more
europepmc +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Transcriptional regulation of the tyrosine aminotransferase gene [PDF]
Boshart, Michael+6 more
core
Transcriptional Tuning: How Auxin Strikes Unique Chords in Gene Regulation. [PDF]
Taylor JS, Bargmann BOR.
europepmc +1 more source