Results 241 to 250 of about 789,865 (294)

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Cellular patterns in Arabidopsis root epidermis emerge from gene regulatory network and diffusion dynamical feedback. [PDF]

NPJ Syst Biol Appl
Castillo-Jiménez A, Garay-Arroyo A, Sánchez MP, Martínez-García JC, Álvarez-Buylla ER.   +4 more
europepmc   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Gene regulatory network prediction using machine learning, deep learning, and hybrid approaches. [PDF]

For Res (Fayettev)
Mummadi ST, Islam MK, Busov V, Wei H.
europepmc   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

LM-Merger: a workflow for merging logical models with an application to gene regulatory network models. [PDF]

BMC Bioinformatics
Li LX, Aguilar B, Gennari J, Qin G.
europepmc   +1 more source

Fatty acid composition and gene regulatory network analysis of pectoral muscle in pigeons across developmental stages. [PDF]

Food Chem (Oxf)
Zheng S, Hou H, Li X, Wang X, Meng Q, Qiao Z, Tu Y, Yang Y, He D, Shen X, Yao J.   +10 more
europepmc   +1 more source

Comparative gene regulatory network mapping of Brassicaceae members with differential drought tolerance

Pandiarajan R, Lin C, Sauer M, Rothballer ST, Marin-de la Rosa N, Schwehn P, Papadopoulou E, Mairhörmann B, Falter-Braun P.   +8 more
europepmc   +1 more source

Defining the role of β-cell IRE1α/XBP1 pathway and its gene regulatory network components in non-obese diabetic mice. [PDF]

Nat Commun
Lee H, Eynullazada K, Ou Q, Shin J, Roy S, Engin F.   +5 more
europepmc   +1 more source

GTAT-GRN: a graph topology-aware attention method with multi-source feature fusion for gene regulatory network inference. [PDF]

Front Genet
Wang S, Zhang L, Gao L, Rao Y, Cui J, Yang L.   +5 more
europepmc   +1 more source