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Estimation of Gene Regulatory Networks

Postdoc Journal, 2013
Complex gene regulatory networks, not individual genes, control cellular function. Genes and gene products act together to determine cellular phenotypes. Estimation of these networks is necessary to understand cellular mechanisms, detect differences in gene regulation between cell types, and predict cellular response to interventions.
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The gene regulatory network

Proceedings of the 10th annual conference on Genetic and evolutionary computation, 2008
This paper proposes a new approach for biologically inspired computing on the basis of Gene Regulatory Networks. These networks are models of genes and dynamic interactions that take place between them. The differential equation representations of such networks resemble neural networks as well as idiotypic networks in immune system.
Sanjoy Das   +4 more
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Gene Regulatory Networks

2007
Two gene regulatory networks inferred from different types of data are considered in this chapter. Gene expression networks are networks inferred from microarray time series data and transcription factor networks are networks obtained from a new genome-wide technique that allows an identification of all of the DNA binding sites for each transcription ...
T. Gregory Dewey, David J. Galas
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Gene Regulatory Networks from Gene Ontology

2013
Gene Ontology (GO) provides a controlled vocabulary and hierarchy of terms to facilitate the annotation of gene functions and molecular attributes. Given a set of genes, a Gene Ontology Network (GON) can be constructed from the corresponding GO annotations and semantic relations among GO terms.
Wenting Liu   +5 more
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Learning Structure of a Gene Regulatory Network

6th IEEE/ACIS International Conference on Computer and Information Science (ICIS 2007), 2007
Application of high-throughput data from microarray experiments is a promising way of finding regulatory relationships between genes. Recently, a causal model approach was presented for learning gene regulatory networks from microarray data. The paper investigates and extends this model by identifying the way in which the causal structure can be best ...
Ramesh Ram, Madhu Chetty
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The gene regulatory networks controlled by estrogens

Molecular and Cellular Endocrinology, 2011
Estrogen signaling occurs widely among vertebrates and in some invertebrates. Estrogen action is mediated by estrogen receptors through the regulation of target gene expression. Estrogen mediated control of gene expression is a complex process including ligand-receptor interactions, receptor-DNA interactions and receptor-cofactor interactions.
Hui, Gao, Karin, Dahlman-Wright
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Gene Regulatory Networks

2019
Gene regulatory networks: methods and protocols , Gene regulatory networks: methods and protocols , کتابخانه‌های دانشگاه ...
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Reconstructing Linear Gene Regulatory Networks

2007
The ability to measure the transcriptional response after a stimulus has drawn much attention to the underlying gene regulatory networks. Here, we evaluate the application of methods to reconstruct gene regulatory networks by applying them to the SOS response of E. coli, the budding yeast cell cycle and in silico models. For each network we define an a
Jochen Supper   +2 more
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Condensing Biochemistry into Gene Regulatory Networks

International Journal of Natural Computing Research, 2014
Gene Regulatory Networks are models of gene regulation. Inferring such model from genome-wide gene-expression measurements is one of the key challenges in modern biology, and a large number of algorithms have been proposed for this task. As there is still much confusion in the current literature as to what precisely Gene Regulatory Networks are, it is ...
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