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CaHoT-GRN: context-aware high-order topology learning for robust single-cell gene regulatory network inference. [PDF]
Yao D, Zhang B, Zhan X, Wang W, Liang N.
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TRENDY: gene regulatory network inference enhanced by transformer. [PDF]
Tian X, Patel Y, Wang Y.
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Dissecting the enhancer gene regulatory network in early Drosophila spermatogenesis. [PDF]
van Nierop Y Sanchez P +21 more
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Improved gene regulatory network inference from single cell data with dropout augmentation. [PDF]
Zhu H, Slonim DK.
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Correction to: Critical assessment of the ability of Boolean threshold models to describe gene regulatory network dynamics. [PDF]
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The Engineering of Gene Regulatory Networks
Annual Review of Biomedical Engineering, 2003▪ Abstract The rapid accumulation of genetic information and advancement of experimental techniques have opened a new frontier in biomedical engineering. With the availability of well-characterized components from natural gene networks, the stage has been set for the engineering of artificial gene regulatory networks with sophisticated computational ...
Mads, Kaern +2 more
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Noise in Gene Regulatory Networks
IEEE Transactions on Automatic Control, 2008Life processes in single cells and at the molecular level are inherently stochastic. Quantifying the noise is, however, far from trivial, as a major contribution comes from intrinsic fluctuations, arising from the randomness in the times between discrete jumps.
Ioannis Lestas +3 more
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Switching Gene Regulatory Networks
2015A fundamental question in biology is how cells change into specific cell types with unique roles throughout development. This process can be viewed as a program prescribing the system dynamics, governed by a network of genetic interactions. Recent experimental evidence suggests that these networks are not fixed but rather change their topology as cells
Yoli Shavit +5 more
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Modeling of Hysteresis in Gene Regulatory Networks
Bulletin of Mathematical Biology, 2012Hysteresis, observed in many gene regulatory networks, has a pivotal impact on biological systems, which enhances the robustness of cell functions. In this paper, a general model is proposed to describe the hysteretic gene regulatory network by combining the hysteresis component and the transient dynamics.
Hu, J., Qin, K.R., Xiang, C., Lee, T.H.
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