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Methods in Molecular Biology, 2019 Gene regulatory networks: methods and protocols , Gene regulatory networks: methods and protocols , کتابخانههای دانشگاه ...
G. Sanguinetti, V. A. Huynh-Thu
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Synchrony in Gene Regulatory Networks
Physica D: Nonlinear phenomena, 2021 We consider two mathematical dynamical models of gene regulatory networks (GRNs) and obtain results on robust synchronization on these dynamical models based on the existing theoretical results in the coupled cell network formalism. We also explore the concepts of quotient networks and network lifting in the context of GRNs which are related to the ...
Aguiar, Manuela A. D. +2 more
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Introduction to gene regulatory networks [PDF]
Proceedings of the Genetic and Evolutionary Computation Conference Companion, 2015 Gene regulatory networks are a central mechanism in the regulation of gene expression in all living organisms? cells. Their functioning is nowadays very well understood: they are based on the production of proteins enhanced or inhibited by other proteins inside and outside the cells. This produces a complex dynamics with which, with the exact same DNA,
Sylvain Cussat-Blanc, Wolfgang Banzhaf
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On Hybrid Gene Regulatory Networks
CoRRIn this work, we study a class of hybrid dynamical systems called hybrid gene regulatory networks (HGRNs) which was proposed to model gene regulatory networks. In HGRNs, there exist well-behaved trajectories that reach a fixed point or converge to a limit cycle, as well as chaotic trajectories that behave non-periodic or indeterministic.
Adrian Wurm, Honglu Sun
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Gene regulatory networks for development [PDF]
Proceedings of the National Academy of Sciences, 2005 The genomic program for development operates primarily by the regulated expression of genes encoding transcription factors and components of cell signaling pathways. This program is executed by cis-regulatory DNAs (e.g., enhancers and silencers) that control gene expression.
Levine, Michael, Davidson, Eric H.
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Integrated module and gene-specific regulatory inference implicates upstream signaling networks. [PDF]
PLoS Computational Biology, 2013 Regulatory networks that control gene expression are important in diverse biological contexts including stress response and development. Each gene's regulatory program is determined by module-level regulation (e.g.
Sushmita Roy +5 more
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Frontiers in Cell and Developmental Biology, 2014 In recent years gene regulatory networks (GRNs) have attracted a lot of interest and many methods have been introduced for their statistical inference from gene expression data. However, despite their popularity, GRNs are widely misunderstood.
Frank eEmmert-Streib +2 more
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Automated Identification of Core Regulatory Genes in Human Gene Regulatory Networks.
PLoS Computational Biology, 2015 Human gene regulatory networks (GRN) can be difficult to interpret due to a tangle of edges interconnecting thousands of genes. We constructed a general human GRN from extensive transcription factor and microRNA target data obtained from public databases.
Vipin Narang +6 more
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Identifying gene regulatory networks in schizophrenia [PDF]
NeuroImage, 2010 The imaging genetics approach to studying the genetic basis of disease leverages the individual strengths of both neuroimaging and genetic studies by visualizing and quantifying the brain activation patterns in the context of genetic background. Brain imaging as an intermediate phenotype can help clarify the functional link among genes, the molecular ...
Steven G. Potkin +10 more
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From time-series transcriptomics to gene regulatory networks: A review on inference methods [PDF]
PLoS Comput. Biol., 2022 Inference of gene regulatory networks has been an active area of research for around 20 years, leading to the development of sophisticated inference algorithms based on a variety of assumptions and approaches.
Malvina Marku, V. Pancaldi
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