Results 31 to 40 of about 946,920 (339)
Discovering study-specific gene regulatory networks. [PDF]
PLoS ONE, 2014 Microarrays are commonly used in biology because of their ability to simultaneously measure thousands of genes under different conditions. Due to their structure, typically containing a high amount of variables but far fewer samples, scalable network ...
Valeria Bo +5 more
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Polygenic Adaptation: Integrating Population Genetics and Gene Regulatory Networks.
Trends in Genetics, 2021 The adaptation of populations to local environments often relies on the selection of optimal values for polygenic traits. Here, we first summarize the results obtained from different quantitative genetics and population genetics models, about the genetic
M. Fagny, F. Austerlitz
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Structure learning for gene regulatory networks.
PLoS Computational Biology, 2023 Inference of biological network structures is often performed on high-dimensional data, yet is hindered by the limited sample size of high throughput "omics" data typically available. To overcome this challenge, often referred to as the "small n, large p
Anthony Federico +3 more
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Gene Self-Expressive Networks as a Generalization-Aware Tool to Model Gene Regulatory Networks
Biomolecules, 2023 Self-expressiveness is a mathematical property that aims at characterizing the relationship between instances in a dataset. This property has been applied widely and successfully in computer-vision tasks, time-series analysis, and to infer underlying ...
Sergio Peignier, Federica Calevro
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Gene-centered regulatory networks [PDF]
Briefings in Functional Genomics, 2009 Differential gene expression plays a critical role in the development and physiology of multicellular organisms. At a 'systems level' (e.g. at the level of a tissue, organ or whole organism), this process can be studied using gene regulatory network (GRN) models that capture physical and regulatory interactions between genes and their regulators.
Arda, H. Efsun, Walhout, Albertha J M
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, 2022 This code accompanies the manuscript "Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root"
Hsu-Che-Wei +2 more
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Supervised Learning of Gene Regulatory Networks [PDF]
Current Protocols in Plant Biology, 2020 AbstractIdentifying the entirety of gene regulatory interactions in a biological system offers the possibility to determine the key molecular factors that affect important traits on the level of cells, tissues, and whole organisms. Despite the development of experimental approaches and technologies for identification of direct binding of transcription ...
Razaghi-Moghadam, Zahra +1 more
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Gradient descent optimization in gene regulatory pathways. [PDF]
PLoS ONE, 2010 BACKGROUND: Gene Regulatory Networks (GRNs) have become a major focus of interest in recent years. Elucidating the architecture and dynamics of large scale gene regulatory networks is an important goal in systems biology.
Mouli Das +2 more
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Gene regulatory networks controlling vertebrate retinal regeneration
Science, 2020 Unlocking retinal regeneration in mice Zebrafish can regenerate damaged retinal tissue, but mice cannot. Hoang et al. found that tracking changes in gene expression and chromatin accessibility upon injury revealed clues as to why retinal glial cells in ...
Thanh V. Hoang +25 more
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Reduction of the chemical master equation for gene regulatory networks using proper generalized decompositions [PDF]
, 2012 The numerical solution of the chemical master equation (CME) governing gene regulatory networks and cell signaling processes remains a challenging task owing to its complexity, exponentially growing with the number of species involved.
CHINESTA SORIA, Francisco +3 more
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