Results 31 to 40 of about 509,029 (282)

Comprehensive information-based differential gene regulatory networks analysis (CIdrgn): Application to gastric cancer and chemotherapy-responsive gene network identification.

open access: yesPLoS ONE, 2023
Biological condition-responsive gene network analysis has attracted considerable research attention because of its ability to identify pathways or gene modules involved in the underlying mechanisms of diseases.
Heewon Park, Seiya Imoto, Satoru Miyano
doaj   +2 more sources

Mutational robustness of gene regulatory networks.

open access: yesPLoS ONE, 2012
Mutational robustness of gene regulatory networks refers to their ability to generate constant biological output upon mutations that change network structure.
Aalt D J van Dijk   +2 more
doaj   +1 more source

Literature-based priors for gene regulatory networks [PDF]

open access: yes, 2009
Motivation: The use of prior knowledge to improve gene regulatory network modelling has often been proposed. In this paper we present the first research on the massive incorporation of prior knowledge from literature for Bayesian network learning of gene
't Hoen, PAC   +3 more
core   +2 more sources

Constructing gene regulatory networks using epigenetic data

open access: yesnpj Systems Biology and Applications, 2021
The biological processes that drive cellular function can be represented by a complex network of interactions between regulators (transcription factors) and their targets (genes).
Abhijeet Rajendra Sonawane   +3 more
doaj   +1 more source

Supervised inference of gene-regulatory networks

open access: yesBMC Bioinformatics, 2008
Background Inference of protein interaction networks from various sources of data has become an important topic of both systems and computational biology.
Vohradsky Jiri, To Cuong C
doaj   +1 more source

GeRNet: a gene regulatory network tool [PDF]

open access: yesBiosystems, 2017
Gene regulatory networks (GRNs) are crucial in every process of life since they govern the majority of the molecular processes. Therefore, the task of assembling these networks is highly important. In particular, the so called model-free approaches have an advantage modeling the complexities of dynamic molecular networks, since most of the gene ...
Julieta Sol Dussaut   +5 more
openaire   +3 more sources

Modeling and identification of alternative folding in regulatory RNAs using context-sensitive HMMS [PDF]

open access: yes, 2006
Recent research on gene regulation has revealed that many noncoding RNAs (ncRNAs) are actively involved in controlling various gene-regulatory networks.
Vaidyanathan, P. P., Yoon, Byung-Jun
core   +3 more sources

Conserved non-coding regulatory signatures in Arabidopsis co-expressed gene modules. [PDF]

open access: yesPLoS ONE, 2012
Complex traits and other polygenic processes require coordinated gene expression. Co-expression networks model mRNA co-expression: the product of gene regulatory networks.
Jacob B Spangler   +4 more
doaj   +1 more source

Master Regulators, Regulatory Networks, and Pathways of Glioblastoma Subtypes [PDF]

open access: yes, 2014
Glioblastoma multiforme (GBM) is the most common malignant brain tumor. GBM samples are classified into subtypes based on their transcriptomic and epigenetic profiles.
  +4 more
core   +3 more sources

Effects of Time Point Measurement on the Reconstruction of Gene Regulatory Networks

open access: yesMolecules, 2010
With the availability of high-throughput gene expression data in the post-genomic era, reconstruction of gene regulatory networks has become a hot topic.
Bairong Shen   +5 more
doaj   +1 more source

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