Results 51 to 60 of about 946,920 (339)
Mutational robustness of gene regulatory networks.
PLoS ONE, 2012 Mutational robustness of gene regulatory networks refers to their ability to generate constant biological output upon mutations that change network structure.
Aalt D J van Dijk +2 more
doaj +1 more source
Gene regulatory networks elucidating huanglongbing disease mechanisms. [PDF]
PLoS ONE, 2013 Next-generation sequencing was exploited to gain deeper insight into the response to infection by Candidatus liberibacter asiaticus (CaLas), especially the immune disregulation and metabolic dysfunction caused by source-sink disruption.
Federico Martinelli +8 more
doaj +1 more source
A method to construct gene regulatory networks to estimate and calculate time delays [PDF]
, 2013 In general, the motive of this research is to infer gene regulatory network in order to clarify the basis consequences of biological process at the molecular level.
Mohamad, Mohd. Saberi, Chai, Suk Phin
core +1 more source
Conserved non-coding regulatory signatures in Arabidopsis co-expressed gene modules. [PDF]
PLoS ONE, 2012 Complex traits and other polygenic processes require coordinated gene expression. Co-expression networks model mRNA co-expression: the product of gene regulatory networks.
Jacob B Spangler +4 more
doaj +1 more source
Survey of Research on Non-homogeneous Gene Regulatory Network Models [PDF]
Jisuanji kexue yu tansuo, 2023 In the field of bioinformatics, the construction of gene regulatory networks is crucial. In recent years, non-homogeneous dynamic Bayesian networks have become a common modeling tool for learning gene regulatory networks from gene expression time-series ...
ZHANG Qianqian, HU Chunling, ZHANG Jiayao, LI Dawei, SHAO Mingyi
doaj +1 more source
Inference on the structure of gene regulatory networks [PDF]
Journal of Theoretical Biology, 2022 In this paper, we conduct theoretical analyses on inferring the structure of gene regulatory networks. Depending on the experimental method and data type, the inference problem is classified into 20 different scenarios. For each scenario, we discuss the problem that with enough data, under what assumptions, what can be inferred about the structure. For
Yue Wang, Zikun Wang
openaire +4 more sources
Dynamic links and evolutionary history in simulated gene regulatory networks
, 2020 In this chapter, we describe the use of evolutionary methods for the in silico generation of artificial gene regulatory networks (GRNs). These usually serve as models for biological networks and can be used for enhancing analysis methods in biology.
Sendhoff, B +3 more
core +1 more source
Time-delayed models of gene regulatory networks [PDF]
, 2015 We discuss different mathematical models of gene regulatory networks as relevant to the onset and development of cancer. After discussion of alternativemodelling approaches, we use a paradigmatic two-gene network to focus on the role played by time ...
S J Hogan (16072466) +3 more
core +2 more sources
Effects of Time Point Measurement on the Reconstruction of Gene Regulatory Networks
Molecules, 2010 With the availability of high-throughput gene expression data in the post-genomic era, reconstruction of gene regulatory networks has become a hot topic.
Bairong Shen +5 more
doaj +1 more source
STAR Protocols, 2022 Summary: Due to a lack of explicit temporal information, it can be challenging to infer gene regulatory networks from clinical transcriptomic data.
Zhaorui Dong, Xiaoqiang Sun
doaj +1 more source