Results 41 to 50 of about 509,029 (282)
STAR Protocols, 2022 Summary: Due to a lack of explicit temporal information, it can be challenging to infer gene regulatory networks from clinical transcriptomic data.
Zhaorui Dong, Xiaoqiang Sun
doaj +1 more source
Dissecting the Biological Motherboard (Systems Biology and Beyond) [PDF]
, 2008 Genome-scale molecular networks, including gene pathways, gene regulatory networks and protein interactions, are central to the investigation of the nascent disciplines of systems biology and bio-complexity.
Abhay Krishna, Ajit Narayanan
core +2 more sources
Gene Regulatory Networks in the Genomics Era
Genomics, Proteomics & Bioinformatics, 2013 The precise regulation of gene expression is critical to the normal development and biological function of all organisms. Dysregulation of gene expression during early development can result in a spectrum of failures ranging from minor defects to the termination of development.
Matthew Loose +3 more
openaire +4 more sources
Model Checking Gene Regulatory Networks [PDF]
, 2015 19 pages, 20 references, 4 ...
Mirco Giacobbe +5 more
openaire +3 more sources
Bayesian variable selection and data integration for biological regulatory networks [PDF]
, 2006 A substantial focus of research in molecular biology are gene regulatory networks: the set of transcription factors and target genes which control the involvement of different biological processes in living cells.
Chen, Guang +2 more
core +6 more sources
Predicting gene regulatory networks from cell atlases
Life Science Alliance, 2020 Integrated single-cell gene regulatory network from three mouse cell atlases captures global and cell type–specific regulatory modules and crosstalk, important for cellular identity.
Andreas Fønss Møller +1 more
doaj +1 more source
Emergence of co-expression in gene regulatory networks.
PLoS ONE, 2021 Transcriptomes are known to organize themselves into gene co-expression clusters or modules where groups of genes display distinct patterns of coordinated or synchronous expression across independent biological samples.
Wencheng Yin +4 more
doaj +1 more source
Stochastic neural network models for gene regulatory networks [PDF]
, 2003 Recent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of genome dynamics by means of mathematical modelling.
Burrage, K., Tian, T.
core +2 more sources
Cellular and Molecular Life SciencesDevelopment is characterized by dynamic changes in gene expression as cells traverse genetic pathways and make lineage-specific commitments. Transcription factors, which drive gene expression, and microRNAs, the largest class of post-transcriptional ...
Fakhira H. Nazki, Cameron P. Bracken
doaj +1 more source
Dynamical methods for target control of biological networks
Royal Society Open Science, 2023 Estimating the influence that individual nodes have on one another in a Boolean network is essential to predict and control the system’s dynamical behaviour, for example, detecting key therapeutic targets to control pathways in models of biological ...
Thomas Parmer, Filippo Radicchi
doaj +1 more source