Results 41 to 50 of about 5,034,704 (247)

Survey of Research on Non-homogeneous Gene Regulatory Network Models [PDF]

Jisuanji kexue yu tansuo, 2023
In the field of bioinformatics, the construction of gene regulatory networks is crucial. In recent years, non-homogeneous dynamic Bayesian networks have become a common modeling tool for learning gene regulatory networks from gene expression time-series ...
ZHANG Qianqian, HU Chunling, ZHANG Jiayao, LI Dawei, SHAO Mingyi
doaj   +1 more source

Correlated fluctuations carry signatures of gene regulatory network dynamics [PDF]

, 2010
The dynamics of transcriptional control involve small numbers of molecules and result in significant fluctuations in protein and mRNA concentrations.
Pakka, V. H., Pakka, Vijayanarasimha H., Prugel-Bennett, Adam, Prugel-Bennett, A., Adam Prügel-Bennett, Dasmahapatra, S., Pakka, Vijayanarasimha, Dasmahapatra, Srinandan, Vijayanarasimha H. Pakka, Srinandan Dasmahapatra   +9 more
core   +1 more source

Effects of Time Point Measurement on the Reconstruction of Gene Regulatory Networks

Molecules, 2010
With the availability of high-throughput gene expression data in the post-genomic era, reconstruction of gene regulatory networks has become a hot topic.
Bairong Shen, Yuanyuan Zhang, Jiajia Chen, Yang Yang, Huangqiong Zhu, Wenying Yan   +5 more
doaj   +1 more source

Inferring disease progression and gene regulatory networks from clinical transcriptomic data using PROB_R

STAR Protocols, 2022
Summary: Due to a lack of explicit temporal information, it can be challenging to infer gene regulatory networks from clinical transcriptomic data.
Zhaorui Dong, Xiaoqiang Sun
doaj   +1 more source

Conserved non-coding regulatory signatures in Arabidopsis co-expressed gene modules. [PDF]

PLoS ONE, 2012
Complex traits and other polygenic processes require coordinated gene expression. Co-expression networks model mRNA co-expression: the product of gene regulatory networks.
Jacob B Spangler, Stephen P Ficklin, Feng Luo, Michael Freeling, F Alex Feltus   +4 more
doaj   +1 more source

Gene Regulatory Networks in the Genomics Era

Genomics, Proteomics & Bioinformatics, 2013
The precise regulation of gene expression is critical to the normal development and biological function of all organisms. Dysregulation of gene expression during early development can result in a spectrum of failures ranging from minor defects to the termination of development.
Matthew Loose, Roger Patient, Xiangdong Fang, Hongxing Lei   +3 more
openaire   +5 more sources

A method to construct gene regulatory networks to estimate and calculate time delays [PDF]

, 2013
In general, the motive of this research is to infer gene regulatory network in order to clarify the basis consequences of biological process at the molecular level.
Mohamad, Mohd. Saberi, Chai, Suk Phin
core   +1 more source

Homeostasis in gene regulatory networks

International Journal of Biomathematics
Gene regulatory networks lie at the heart of many important intracellular signal transduction processes. A Gene Regulatory Network (GRN) is abstractly defined as a directed graph, where the nodes represent genes and the edges represent the causal regulatory interactions between genes. It can be used to construct mathematical models describing the time-
Fernando Antoneli, Martin Golubitsky, Jiaxin Jin, Ian Stewart   +3 more
openaire   +2 more sources

Predicting gene regulatory networks from cell atlases

Life Science Alliance, 2020
Integrated single-cell gene regulatory network from three mouse cell atlases captures global and cell type–specific regulatory modules and crosstalk, important for cellular identity.
Andreas Fønss Møller, Kedar Nath Natarajan   +1 more
doaj   +1 more source

Emergence of co-expression in gene regulatory networks.

PLoS ONE, 2021
Transcriptomes are known to organize themselves into gene co-expression clusters or modules where groups of genes display distinct patterns of coordinated or synchronous expression across independent biological samples.
Wencheng Yin, Luis Mendoza, Jimena Monzon-Sandoval, Araxi O Urrutia, Humberto Gutierrez   +4 more
doaj   +1 more source