Results 41 to 50 of about 6,728,627 (290)
Conserved non-coding regulatory signatures in Arabidopsis co-expressed gene modules. [PDF]
PLoS ONE, 2012 Complex traits and other polygenic processes require coordinated gene expression. Co-expression networks model mRNA co-expression: the product of gene regulatory networks.
Jacob B Spangler +4 more
doaj +1 more source
STAR Protocols, 2022 Summary: Due to a lack of explicit temporal information, it can be challenging to infer gene regulatory networks from clinical transcriptomic data.
Zhaorui Dong, Xiaoqiang Sun
doaj +1 more source
Model Checking Gene Regulatory Networks [PDF]
, 2015 19 pages, 20 references, 4 ...
Mirco Giacobbe +5 more
openaire +5 more sources
Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms [PDF]
, 2009 Baumbach J, Rahmann S, Tauch A. Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms. BMC Systems Biology.
Sven Rahmann +5 more
core +1 more source
Emergence of co-expression in gene regulatory networks.
PLoS ONE, 2021 Transcriptomes are known to organize themselves into gene co-expression clusters or modules where groups of genes display distinct patterns of coordinated or synchronous expression across independent biological samples.
Wencheng Yin +4 more
doaj +1 more source
Gene Regulatory Networks in the Genomics Era
Genomics, Proteomics & Bioinformatics, 2013 The precise regulation of gene expression is critical to the normal development and biological function of all organisms. Dysregulation of gene expression during early development can result in a spectrum of failures ranging from minor defects to the termination of development.
Matthew Loose +3 more
openaire +5 more sources
Modelling nonstationary gene regulatory processes [PDF]
, 2010 An important objective in systems biology is to infer gene regulatory networks from postgenomic data, and dynamic Bayesian networks have been widely applied as a popular tool to this end.
Husmeier, D. +5 more
core +1 more source
Cellular and Molecular Life SciencesDevelopment is characterized by dynamic changes in gene expression as cells traverse genetic pathways and make lineage-specific commitments. Transcription factors, which drive gene expression, and microRNAs, the largest class of post-transcriptional ...
Fakhira H. Nazki, Cameron P. Bracken
doaj +1 more source
Homeostasis in gene regulatory networks
International Journal of BiomathematicsGene regulatory networks lie at the heart of many important intracellular signal transduction processes. A Gene Regulatory Network (GRN) is abstractly defined as a directed graph, where the nodes represent genes and the edges represent the causal regulatory interactions between genes. It can be used to construct mathematical models describing the time-
Fernando Antoneli +3 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source