Results 61 to 70 of about 509,029 (282)

CoryneRegNet 4.0 – A reference database for corynebacterial gene regulatory networks

open access: yesBMC Bioinformatics, 2007
Background Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of microorganisms deduced from literature-derived knowledge, computer predictions ...
Baumbach Jan
doaj   +1 more source

A publish-subscribe model of genetic networks. [PDF]

open access: yesPLoS ONE, 2008
We present a simple model of genetic regulatory networks in which regulatory connections among genes are mediated by a limited number of signaling molecules.
Brett Calcott   +2 more
doaj   +1 more source

Network Inference from Gene Expression Data with Distance Correlation and Network Topology Centrality

open access: yesAlgorithms, 2021
The reconstruction of gene regulatory networks based on gene expression data can effectively uncover regulatory relationships between genes and provide a deeper understanding of biological control processes.
Kuan Liu   +3 more
doaj   +1 more source

Existence of Oscillations in Cyclic Gene Regulatory Networks with Time Delay [PDF]

open access: yes, 2012
This paper is concerned with conditions for the existence of oscillations in gene regulatory networks with negative cyclic feedback, where time delays in transcription, translation and translocation process are explicitly considered.
Hara, Shinji   +2 more
core  

Exact reconstruction of gene regulatory networks using compressive sensing. [PDF]

open access: yes, 2014
BackgroundWe consider the problem of reconstructing a gene regulatory network structure from limited time series gene expression data, without any a priori knowledge of connectivity.
Chang, Young Hwan   +2 more
core   +1 more source

Cardiac gene regulatory networks in Drosophila [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2009
The Drosophila system has proven a powerful tool to help unlock the regulatory processes that occur during specification and differentiation of the embryonic heart. In this review, we focus upon a temporal analysis of the molecular events that result in heart formation in Drosophila, with a particular emphasis upon how genomic and other cutting-edge ...
Anton L, Bryantsev, Richard M, Cripps
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

XGRN: Reconstruction of Biological Networks Based on Boosted Trees Regression

open access: yesComputation, 2021
In Systems Biology, the complex relationships between different entities in the cells are modeled and analyzed using networks. Towards this aim, a rich variety of gene regulatory network (GRN) inference algorithms has been developed in recent years ...
Georgios N. Dimitrakopoulos
doaj   +1 more source

On Hybrid Gene Regulatory Networks

open access: yesCoRR
In this work, we study a class of hybrid dynamical systems called hybrid gene regulatory networks (HGRNs) which was proposed to model gene regulatory networks. In HGRNs, there exist well-behaved trajectories that reach a fixed point or converge to a limit cycle, as well as chaotic trajectories that behave non-periodic or indeterministic.
Adrian Wurm, Honglu Sun
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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