Results 21 to 30 of about 5,034,704 (247)

Chaotic motifs in gene regulatory networks. [PDF]

PLoS ONE, 2012
Chaos should occur often in gene regulatory networks (GRNs) which have been widely described by nonlinear coupled ordinary differential equations, if their dimensions are no less than 3. It is therefore puzzling that chaos has never been reported in GRNs
Zhaoyang Zhang, Weiming Ye, Yu Qian, Zhigang Zheng, Xuhui Huang, Gang Hu   +5 more
doaj   +1 more source

Supervised Learning of Gene Regulatory Networks [PDF]

Current Protocols in Plant Biology, 2020
AbstractIdentifying the entirety of gene regulatory interactions in a biological system offers the possibility to determine the key molecular factors that affect important traits on the level of cells, tissues, and whole organisms. Despite the development of experimental approaches and technologies for identification of direct binding of transcription ...
Razaghi-Moghadam, Zahra, Nikoloski, Zoran   +1 more
openaire   +4 more sources

Gradient descent optimization in gene regulatory pathways. [PDF]

PLoS ONE, 2010
BACKGROUND: Gene Regulatory Networks (GRNs) have become a major focus of interest in recent years. Elucidating the architecture and dynamics of large scale gene regulatory networks is an important goal in systems biology.
Mouli Das, Subhasis Mukhopadhyay, Rajat K De   +2 more
doaj   +1 more source

Gene regulatory networks for development [PDF]

Proceedings of the National Academy of Sciences, 2005
The genomic program for development operates primarily by the regulated expression of genes encoding transcription factors and components of cell signaling pathways. This program is executed by cis-regulatory DNAs (e.g., enhancers and silencers) that control gene expression.
Levine, Michael, Davidson, Eric H.
openaire   +4 more sources

Reduction of the chemical master equation for gene regulatory networks using proper generalized decompositions [PDF]

, 2012
The numerical solution of the chemical master equation (CME) governing gene regulatory networks and cell signaling processes remains a challenging task owing to its complexity, exponentially growing with the number of species involved.
CHINESTA SORIA, Francisco, Chinesta, Francisco, CUETO, Elias, AMMAR, Amine   +3 more
core   +1 more source

Artificial Gene Regulatory Networks—A Review [PDF]

Artificial Life, 2019
In nature, gene regulatory networks are a key mediator between the information stored in the DNA of living organisms (their genotype) and the structural and behavioral expression this finds in their bodies, surviving in the world (their phenotype). They integrate environmental signals, steer development, buffer stochasticity, and allow evolution to ...
Cussat-Blanc, Sylvain, Harrington, Kyle, Banzhaf, Wolfgang   +2 more
openaire   +5 more sources

Filtering for nonlinear genetic regulatory networks with stochastic disturbances [PDF]

, 2008
In this paper, the filtering problem is investigated for nonlinear genetic regulatory networks with stochastic disturbances and time delays, where the nonlinear function describing the feedback regulation is assumed to satisfy the sector condition, the ...
Liu, X, Wang, Z, Fraser, K, Lam, J, Wei, G   +4 more
core   +3 more sources

RENGE infers gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations

Communications Biology, 2023
Single-cell RNA-seq analysis coupled with CRISPR-based perturbation has enabled the inference of gene regulatory networks with causal relationships.
Masato Ishikawa, Seiichi Sugino, Yoshie Masuda, Yusuke Tarumoto, Yusuke Seto, Nobuko Taniyama, Fumi Wagai, Yuhei Yamauchi, Yasuhiro Kojima, Hisanori Kiryu, Kosuke Yusa, Mototsugu Eiraku, Atsushi Mochizuki   +12 more
doaj   +1 more source

Dynamic Bayesian networks in molecular plant science: inferring gene regulatory networks from multiple gene expression time series [PDF]

, 2011
To understand the processes of growth and biomass production in plants, we ultimately need to elucidate the structure of the underlying regulatory networks at the molecular level.
Dondelinger, F., Husmeier, D., Dondelinger, Frank, Dirk Husmeier, Frank Dondelinger, Husmeier, Dirk, Lebre, S., Sophie Lèbre, Lèbre, Sophie   +8 more
core   +1 more source

Gene regulatory networks elucidating huanglongbing disease mechanisms. [PDF]

PLoS ONE, 2013
Next-generation sequencing was exploited to gain deeper insight into the response to infection by Candidatus liberibacter asiaticus (CaLas), especially the immune disregulation and metabolic dysfunction caused by source-sink disruption.
Federico Martinelli, Russell L Reagan, Sandra L Uratsu, My L Phu, Ute Albrecht, Weixiang Zhao, Cristina E Davis, Kim D Bowman, Abhaya M Dandekar   +8 more
doaj   +1 more source