We address gene selection and machine learning methods for cancer classification using microarray gene expression data. Due to the high dimensionality of microarray data, traditional gene selection algorithms are filter-based, focusing on intrinsic ...
Songyot Nakariyakul
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Gene duplication and an accelerated evolutionary rate in 11S globulin genes are associated with higher protein synthesis in dicots as compared to monocots [PDF]
Background: Seed storage proteins are a major source of dietary protein, and the content of such proteins determines both the quantity and quality of crop yield.
Dunwell, Jim +3 more
core +2 more sources
The recent advance in the microarray data analysis makes it easy to simultaneously measure the expression levels of several thousand genes. These levels can be used to distinguish cancerous tissues from normal ones.
Ahmed Bir-Jmel +2 more
semanticscholar +1 more source
Gene-Wide Identification of Episodic Selection [PDF]
We present BUSTED, a new approach to identifying gene-wide evidence of episodic positive selection, where the non-synonymous substitution rate is transiently greater than the synonymous rate. BUSTED can be used either on an entire phylogeny (without requiring an a priori hypothesis regarding which branches are under positive selection) or on a pre ...
Murrell, Ben +11 more
openaire +3 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
New Bio-Marker Gene Discovery Algorithms for Cancer Gene Expression Profile
Several hybrid gene selection algorithms for cancer classification that employ bio-inspired evolutionary wrapper algorithm have been proposed in the literature and show good classification accuracy.
Nada Almugren, Hala M. Alshamlan
doaj +1 more source
Gene expression profiles of tissues treated with drugs have recently been used to infer clinical outcomes. Although this method is often successful from the application point of view, gene expression altered by drugs is rarely analyzed in detail, because
Yh. Taguchi, Turki Turki
doaj +1 more source
A Novel Single Nucleotide Polymorphism in Exon 4 of Insulin-Like Growth Factor-1 Associated with Production Traits in Bali Cattle [PDF]
Insulin-like growth factor-1 (IGF-1) is one of the gene candidates that can be used in selection strategy by using DNA markers (marker assisted selection).
Arman, C. (C) +4 more
core
Primer selection impacts specific population abundances but not community dynamics in a monthly time-series 16S rRNA gene amplicon analysis of coastal marine bacterioplankton. [PDF]
Primers targeting the 16S small subunit ribosomal RNA marker gene, used to characterize bacterial and archaeal communities, have recently been re-evaluated for marine planktonic habitats.
Carlson, Craig A +3 more
core +1 more source

