Results 101 to 110 of about 2,115,238 (295)

Detecting signatures of balancing selection to identify targets of anti-parasite immunity.

, 2010
Parasite antigen genes might evolve under frequency-dependent immune selection. The distinctive patterns of polymorphism that result can be detected using population genetic methods that test for signatures of balancing selection, allowing genes encoding
Conway, David J, Weedall, Gareth D
core   +1 more source

Selection-driven gene loss in bacteria. [PDF]

PLoS Genetics, 2012
Gene loss by deletion is a common evolutionary process in bacteria, as exemplified by bacteria with small genomes that have evolved from bacteria with larger genomes by reductive processes.
Sanna Koskiniemi, Song Sun, Otto G Berg, Dan I Andersson   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Genomically Selected Genes Associated with a High Rate of Egg Production in Puan Panjiang Black-Bone Chickens

Animals
Puan Panjiang black-bone chickens are renowned for their distinctive traits, deep black coloration, and high-quality protein content, making them a focus of genetic research due to their unique egg-laying abilities. In this study, 110 Puan Panjiang black-
Xiaomeng Miao, Zhiying Huang, Jia Liu, Li Zhang, Yulong Feng, Yalan Zhang, Diyan Li, Zhonghua Ning   +7 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A cDNA subtraction approach to isolate male-specific genes from Ceratitis capitata : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University [PDF]

, 2003
The Mediterranean fruit fly, Ceraritis capitata (medfly), is a significant world wide agricultural pest. Sterile Insect Technique (SIT) is a biological method that has been used to control medfly successfully in several parts of the world for around two ...
Hills, Simon Francis Kahu
core  

Cancer Classification in Microarray Data using a Hybrid Selective Independent Component Analysis and ϑ-Support Vector Machine Algorithm

Journal of Medical Signals and Sensors, 2014
Microarray data have an important role in identification and classification of the cancer tissues. Having a few samples of microarrays in cancer researches is always one of the most concerns which lead to some problems in designing the classifiers.
Hamidreza Saberkari, Mousa Shamsi, Mahsa Joroughi, Faegheh Golabi, Mohammad Hossein Sedaaghi   +4 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Positive Selection on Mammalian Immune Genes—Effects of Gene Function and Selective Constraint

Molecular Biology and Evolution
Abstract Genome-wide analyses of various taxa have repeatedly shown that immune genes are important targets of positive selection. However, little is known about what factors determine which immune genes are under positive selection. To address this question, we here focus on the mammalian immune system and investigate the importance of ...
Mridula Nandakumar, Max Lundberg, Fredric Carlsson, Lars Råberg   +3 more
openaire   +3 more sources