Results 111 to 120 of about 1,213,334 (312)
IEEE Access, 2019 The emergence of DNA Microarray technology has enabled researchers to analyze the expression level of thousands of genes simultaneously. The Microarray data analysis is the process of finding the most informative genes as well as remove redundant and ...
Nada Almugren, Hala Alshamlan
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Selection-driven gene loss in bacteria. [PDF]
PLoS Genetics, 2012 Gene loss by deletion is a common evolutionary process in bacteria, as exemplified by bacteria with small genomes that have evolved from bacteria with larger genomes by reductive processes.
Sanna Koskiniemi +3 more
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Deep gene selection method to select genes from microarray datasets for cancer classification [PDF]
BMC Bioinformatics, 2019 Abstract Background Microarray datasets consist of complex and high-dimensional samples and genes, and generally the number of samples is much smaller than the number of genes. Due to this data imbalance, gene selection is a demanding task for microarray expression data analysis. Results
Russul Alanni +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A population genetics model of marker-assisted selection [PDF]
, 1997 A deterministic two-loci model was developed to predict genetic response to marker-assisted selection (MAS) in one generation and in multiple generations.
Luo, Z. W. +4 more
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Journal of Medical Signals and Sensors, 2014 Microarray data have an important role in identification and classification of the cancer tissues. Having a few samples of microarrays in cancer researches is always one of the most concerns which lead to some problems in designing the classifiers.
Hamidreza Saberkari +4 more
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AnimalsPuan Panjiang black-bone chickens are renowned for their distinctive traits, deep black coloration, and high-quality protein content, making them a focus of genetic research due to their unique egg-laying abilities. In this study, 110 Puan Panjiang black-
Xiaomeng Miao +7 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Development of a positive-negative selection procedure for gene targeting in fish cells [PDF]
, 2002 The gene targeting technique is a powerful tool for analyzing functions of cloned genes and for generating transgenic animals with site-directed integration of foreign genes.
Hong, YH, Natl Univ Singapore, Dept Biol Sci, 10 Kent Ridge Crescent, Singapore 119260, Singapore +3 more
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