Results 51 to 60 of about 11,201,470 (335)
Variable selection for BART: An application to gene regulation [PDF]
, 2014 We consider the task of discovering gene regulatory networks, which are defined as sets of genes and the corresponding transcription factors which regulate their expression levels. This can be viewed as a variable selection problem, potentially with high
Bleich, Justin +3 more
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IEEE Access, 2020 Microarray data play a huge role in recognizing a proper cancer diagnosis and classification. In most microarray data set consist of thousands of genes, but the majority number of genes are irrelevant to the diseases.
M. Othman +2 more
semanticscholar +1 more source
Lethal Gene Drive Selects Inbreeding [PDF]
, 2016 AbstractThe use of ‘selfish’ gene drive systems to suppress or even extinguish populations has been proposed on theoretical grounds for almost half a century. Creating these genes has recently become possible with CRISPR technology. One seemingly feasible approach, originally proposed by Burt, is to create a homing endonuclease gene (HEG) that inserts ...
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A conditional marker gene allowing both positive and negative selection in plants [PDF]
, 2004 Selectable markers enable transgenic plants or cells to be identified after transformation. They can be divided into positive and negative markers conferring a selective advantage or disadvantage, respectively.
Erikson, Oskar +2 more
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Identification and mapping of the novel apple scab resistance gene Vd3 [PDF]
, 2009 Apple scab, caused by the fungal pathogen Venturia inaequalis, is one of the most devastating diseases for the apple growing in temperate zones with humid springs and summers.
Groenwold, R. +7 more
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A Novel Method to Efficiently Highlight Nonlinearly Expressed Genes
Frontiers in Genetics, 2020 For precision medicine, there is a need to identify genes that accurately distinguish the physiological state or response to a particular therapy, but this can be challenging.
Qifei Wang +7 more
doaj +1 more source
Assortative Mating By Diet In A Phenotypically Unimodal But Ecologically Variable Population Of Stickleback [PDF]
, 2008 Speciation with gene flow may be driven by a combination of positive assortative mating and disruptive selection, particularly if selection and assortative mating act on the same trait, eliminating recombination between ecotype and mating type ...
Bolnick, Daniel I., Snowberg, Lisa K.
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Evaluation of gene selection metrics for tumor cell classification
Genetics and Molecular Biology, 2004 Gene expression profiles contain the expression level of thousands of genes. Depending on the issue under investigation, this large amount of data makes analysis impractical. Thus, it is important to select subsets of relevant genes to work with.
Katti Faceli +2 more
doaj +1 more source
Hybrid Symmetrical Uncertainty and Reference Set Harmony Search Algorithm for Gene Selection Problem
Mathematics, 2022 Selecting the most miniature possible set of genes from microarray datasets for clinical diagnosis and prediction is one of the most challenging machine learning tasks. A robust gene selection technique is required to identify the most significant subset
Salam Salameh Shreem +3 more
doaj +1 more source
Bayesian variable selection for hierarchical gene–environment and gene–gene interactions [PDF]
Human Genetics, 2014 We propose a Bayesian hierarchical mixture model framework that allows us to investigate the genetic and environmental effects, gene by gene interactions and gene by environment interactions in the same model. Our approach incorporates the natural hierarchical structure between the main effects and interaction effects into a mixture model, such that ...
Changlu, Liu +2 more
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