Results 11 to 20 of about 649,536 (308)

Identification of a Five-Gene Signature for Predicting Survival in Malignant Pleural Mesothelioma Patients

Frontiers in Genetics, 2020
Malignant pleural mesothelioma (MPM), predominantly caused by asbestos exposure, is a highly aggressive cancer with poor prognosis. The staging systems currently used in clinics is inadequate in evaluating the prognosis of MPM. In this study, a five-gene
Yiyang Bai, Xiao Wang, Jia Hou, Luying Geng, Xuan Liang, Zhiping Ruan, Hui Guo, Kejun Nan, Kejun Nan, Lili Jiang   +9 more
doaj   +1 more source

An 18-gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer. [PDF]

PLoS ONE, 2014
AIMS: Vascular invasion by tumor cells is known to be important for cancer progression. By microarray and qPCR analyses, we earlier identified an 18-gene signature associated with vascular involvement in endometrial cancer.
Monica Mannelqvist, Elisabeth Wik, Ingunn M Stefansson, Lars A Akslen   +3 more
doaj   +1 more source

Transcriptomic profiling of peroxisome-related genes reveals a novel prognostic signature in hepatocellular carcinoma

Genes and Diseases, 2022
Emerging evidence suggests that peroxisomes play a role in the regulation of tumorigenesis and cancer progression. However, the prognostic value of peroxisome-related genes has been rarely investigated.
Liewang Qiu, Ke Zhan, Kija Malale, Xiaoling Wu, Zhechuan Mei   +4 more
doaj   +1 more source

Bioinformatic Analysis for the Validation of Novel Biomarkers for Cancer Diagnosis and Drug Sensitivity [PDF]

, 2015
Background: The genetic control of tumour progression presents the opportunity for bioinformatics and gene expression data to be used as a basis for tumour grading.
Lockwood, Laura Anne Rebecca
core   +2 more sources

A robust six-gene prognostic signature for prediction of both disease-free and overall survival in non-small cell lung cancer

Journal of Translational Medicine, 2019
Background The high mortality of patients with non-small cell lung cancer (NSCLC) emphasizes the necessity of identifying a robust and reliable prognostic signature for NSCLC patients.
Shuguang Zuo, Min Wei, Hailin Zhang, Anxian Chen, Junhua Wu, Jiwu Wei, Jie Dong   +6 more
doaj   +1 more source

Identification of a novel six‐gene signature with potential prognostic and therapeutic value in cervical cancer

Cancer Medicine, 2021
Introduction Cervical cancer has high mortality, high recurrence and poor prognosis. Although prognostic biomarkers such as clinicopathological features have been proposed, their accuracy and precision are far from satisfactory.
Xinyu Qu, Zhiwen Shi, Jingjing Guo, Chenyan Guo, Junjun Qiu, Keqin Hua   +5 more
doaj   +1 more source

Prognostic Signatures of Metabolic Genes and Metabolism-Related Long Non-coding RNAs Accurately Predict Overall Survival for Osteosarcoma Patients

Frontiers in Cell and Developmental Biology, 2021
In this study, we identified eight survival-related metabolic genes in differentially expressed metabolic genes by univariate Cox regression analysis based on the therapeutically applicable research to generate effective treatments (n = 84) data set and ...
Gong Chao-yang, Gong Chao-yang, Tang Rong, Shi Yong-qiang, Shi Yong-qiang, Liu Tai-cong, Liu Tai-cong, Zhou Kai-sheng, Nan Wei, Zhang Hai-hong   +9 more
doaj   +1 more source

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures [PDF]

, 2011
Background: Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers.
Ahr, André, Gätje, Regine, Hanker, Lars, Holtrich, Uwe, Iwamoto, Takayuki, Karn, Thomas, Kaufmann, Manfred, Liedtke, Cornelia, Müller, Volkmar, Pusztai, Lajos, Rody, Achim, Ruckhäberle, Eugen, Schmidt, Marcus, Shiang, Christine Y., Solbach, Christine   +14 more
core   +1 more source

Identification of a six-gene signature predicting overall survival for hepatocellular carcinoma

Cancer Cell International, 2019
Background Hepatocellular carcinoma (HCC) remains a major challenge for public health worldwide. Considering the great heterogeneity of HCC, more accurate prognostic models are urgently needed.
Gao-Min Liu, Hua-Dong Zeng, Cai-Yun Zhang, Ji-Wei Xu   +3 more
doaj   +1 more source

Construction and validation of a seven-gene signature for predicting overall survival in patients with kidney renal clear cell carcinoma via an integrated bioinformatics analysis

Animal Cells and Systems, 2020
Kidney renal clear cell carcinoma (KIRC) remains a significant challenge worldwide because of its poor prognosis and high mortality rate, and accurate prognostic gene signatures are urgently required for individual therapy.
Huiming Jiang, Haibin Chen, Nanhui Chen
doaj   +1 more source