Results 21 to 30 of about 631,661 (355)
Frontiers in Cell and Developmental Biology, 2021 In this study, we identified eight survival-related metabolic genes in differentially expressed metabolic genes by univariate Cox regression analysis based on the therapeutically applicable research to generate effective treatments (n = 84) data set and ...
Gong Chao-yang +9 more
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Bioinformatic Analysis for the Validation of Novel Biomarkers for Cancer Diagnosis and Drug Sensitivity [PDF]
, 2015 Background: The genetic control of tumour progression presents the opportunity for bioinformatics and gene expression data to be used as a basis for tumour grading.
Lockwood, Laura Anne Rebecca
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Gene Signatures Revisited [PDF]
JNCI Journal of the National Cancer Institute, 2012 The three-gene model of Haibe-Kains et al. (1) in this issue of the Journal continues a recent trend (2–4) in which a gene signature with only a few genes classifies cancer specimens as well or better than signatures with many more genes. Given that cancer cells involve large numbers of genetic mutations (5), why should a signature with only few genes ...
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A Prognostic Gene Signature for Hepatocellular Carcinoma
Frontiers in Oncology, 2022 Hepatocellular carcinoma is the third most common cause of cancer-related deaths in China and immune-based therapy can improve patient outcomes. In this study, we investigated the relationship between immunity-associated genes and hepatocellular carcinoma from the prognostic perspective.
Rong Chen +6 more
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Journal of Translational Medicine, 2019 Background The high mortality of patients with non-small cell lung cancer (NSCLC) emphasizes the necessity of identifying a robust and reliable prognostic signature for NSCLC patients.
Shuguang Zuo +6 more
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Cancer Medicine, 2021 Introduction Cervical cancer has high mortality, high recurrence and poor prognosis. Although prognostic biomarkers such as clinicopathological features have been proposed, their accuracy and precision are far from satisfactory.
Xinyu Qu +5 more
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Genes and Diseases, 2022 Emerging evidence suggests that peroxisomes play a role in the regulation of tumorigenesis and cancer progression. However, the prognostic value of peroxisome-related genes has been rarely investigated.
Liewang Qiu +4 more
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Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures [PDF]
, 2011 Background: Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers.
Ahr, André +14 more
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Identification of a six-gene signature predicting overall survival for hepatocellular carcinoma
Cancer Cell International, 2019 Background Hepatocellular carcinoma (HCC) remains a major challenge for public health worldwide. Considering the great heterogeneity of HCC, more accurate prognostic models are urgently needed.
Gao-Min Liu +3 more
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Animal Cells and Systems, 2020 Kidney renal clear cell carcinoma (KIRC) remains a significant challenge worldwide because of its poor prognosis and high mortality rate, and accurate prognostic gene signatures are urgently required for individual therapy.
Huiming Jiang, Haibin Chen, Nanhui Chen
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