Results 241 to 250 of about 7,554,622 (397)

Implications of Endogenous Small Regulatory RNAs Survey in Mollusks on Gene Silencing Approaches. [PDF]

Mar Biotechnol (NY)
Von Eiff C, Schueng Zancanela B, Gima M, Quito K, Kotikalapudi M, Valdivia S, Santos-Ortega Y, Flynt AS.   +7 more
europepmc   +1 more source

Regulation of neural gene transcription by optogenetic inhibition of the RE1-silencing transcription factor

, 2015
Francesco Paonessa, Stefania Criscuolo, Silvio Sacchetti, Davide Amoroso, Helena Scarongella, Federico Pecoraro Bisogni, Emanuele Carminati, Giacomo Pruzzo, Luca Maragliano, Fabrizia Cesca, Fabio Benfenati   +10 more
openalex   +2 more sources

Dysregulation of microRNA biogenesis and gene silencing in cancer

Science Signaling, 2015
A. Hata, J. Lieberman
semanticscholar   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

[Retracted] Effects of TLR4 gene silencing on the proliferation and apotosis of hepatocarcinoma HEPG2 cells. [PDF]

Oncol Lett
Liu Y, Li T, Xu Y, Xu E, Zhou M, Wang B, Shen J.   +6 more
europepmc   +1 more source

Viral Virulence Protein Suppresses RNA Silencing–Mediated Defense but Upregulates the Role of MicroRNA in Host Gene Expression[W] [PDF]

, 2004
Jun Chen, Wan Xiang Li, Daoxin Xie, Jinrong Peng, Shou‐Wei Ding   +4 more
openalex   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

RNAi-mediated gene silencing of a 26S proteasome subunit increases mortality of the Japanese beetle Popillia japonica. [PDF]

Pest Manag Sci
Lucetti G, Abbà S, Pesavento G, Fanelli E, De Luca F, Battagini E, Cazzaniga S, Ballottari M, Frizzon D, Mori N, Galetto L.   +10 more
europepmc   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source

Chromosomal and Plasmid-Based CRISPRi Platforms for Conditional Gene Silencing in <i>Lactococcus lactis</i>. [PDF]

Int J Mol Sci
Huang C, Liu M, Kok J.
europepmc   +1 more source