Results 251 to 260 of about 452,517 (308)

Correction to "Strategic Timing of Gene Silencing: Cellular Kinetics-Based Administration of siRNA for Optimized Photothermal Cancer Treatment". [PDF]

Adv Sci (Weinh)
Fang T, Li L, Tariq Muhseen Z, Lane LA, Cai H, Butch CJ, Wang Y.   +6 more
europepmc   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

mRNA-engineered CRISPR-Cas epigenetic editors enable durable and efficient gene silencing <i>in vivo</i>. [PDF]

Innovation (Camb)
Xu C, Zeng C, Wang M, Wei X, Song M, Liu X, Wang W, Chen Q, Ji X, Luo P, Ma L, Sun Y, Gou H, Zhu Z, Li X, Lv YX, Liu P, Zhu JK.   +17 more
europepmc   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

Effective Gene Silencing in Plants by Synthetic Trans-Acting siRNAs Derived From Minimal Precursors. [PDF]

Bio Protoc
Cisneros AE, Alarcia A, Juárez-Molina M, Carbonell A.   +3 more
europepmc   +1 more source

Gene function revealed at the moment of stochastic gene silencing [PDF]

Commun Biol
Gupta S, Cai JJ.
europepmc   +1 more source

Carbon Dots and mesoporous silica nanocomposites improve spray-induced gene silencing to suppress plant RNA and DNA viruses. [PDF]

Sci Rep
Zarrabi S, Rangel C, Martínez-Campos E, Delgado-Martín J, Arpanaei A, Shams-Bakhsh M, Velasco L.   +6 more
europepmc   +1 more source

Gene silencing in plants by artificial small RNAs derived from minimal precursors and expressed via tobacco rattle virus. [PDF]

Plant Mol Biol
Juárez-Molina M, Alarcia A, Primc A, Ortega-Miralles I, Cisneros AE, Carbonell A.   +5 more
europepmc   +1 more source

Strategic Timing of Gene Silencing: Cellular Kinetics-Based Administration of siRNA for Optimized Photothermal Cancer Treatment. [PDF]

Adv Sci (Weinh)
Fang T, Li L, Tariq Muhseen Z, Lane LA, Cai H, Butch CJ, Wang Y.   +6 more
europepmc   +1 more source

A dual-functional cobalt ferrite nanocomplex for targeted cisplatin prodrug delivery and MALAT1 gene silencing in gastric cancer cells. [PDF]

Sci Rep
Doryani F, Ahmadi A, Nikmanesh H, Azami F, Ghasemi A.   +4 more
europepmc   +1 more source