[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer <i>in vitro</i> and <i>in vivo</i>. [PDF]
Mol Med RepChang L, Gong F, Cui Y.
europepmc +1 more source
Development of <i>in vitro</i> potency assays for AAV-based gene silencing therapies targeting FSHD and CMT1A. [PDF]
Mol Ther AdvMcCoy J +5 more
europepmc +1 more source
Host-Induced Gene Silencing of <i>SmDSR32</i> Enhances Wheat Defense Against <i>Sitobion miscanthi</i>. [PDF]
Curr Issues Mol BiolZhang J +6 more
europepmc +1 more source
Chromosome compartment assembly is essential for subtelomeric gene silencing in trypanosomes. [PDF]
Nat CommunAntunes LB +3 more
europepmc +1 more source
Gene silencing versus protein stabilization in transthyretin amyloid cardiomyopathy: contextualizing the HELIOS-B results and the road to precision agent selection. [PDF]
Ann Med Surg (Lond)Khan SA, Ali T, Ul Haque MS, Qamar MA.
europepmc +1 more source
Virus-induced gene silencing in <i>Dianthus</i> by an apple latent spherical virus vector system. [PDF]
Plant Biotechnol (Tokyo)Tanase K, Kasajima I, Yoshikawa N.
europepmc +1 more source
Related searches:
About two years ago, it was recognized that introduction of double-stranded RNA (dsRNA) had a potent effect on gene expression, in particular on mRNA stability. Since then, this process has been found to occur in many different organisms, and to bear a strong resemblance to a previously recognized process in plants, called cosuppression.
R H, Plasterk, R F, Ketting
openaire +2 more sources
Silencing of cardiac genes by RNA interference (RNAi) has developed into a powerful new method to treat cardiac diseases. Small interfering (si)RNAs are the inducers of RNAi, but cultured primary cardiomyocytes and heart are highly resistant to siRNA transfection.
Henry, Fechner +3 more
openaire +2 more sources
Gene silencing has evolved in a broad range of organisms probably as defense mechanisms against invasive nucleic acids. Two major strategies are utilized. Transcriptional gene silencing (TGS) acts to prevent RNA synthesis and posttranscriptional gene silencing (PTGS) acts to degrade existing RNA.
openaire +2 more sources
“After such a survey one could readily come to the conclusion that the basis of the phenomenon is much too complex for profitable continuation of its investigation at this time”. [W.K. Baker (1968), in a review entitled “Position-effect variegation.”]
openaire +2 more sources