Results 261 to 270 of about 7,554,622 (397)

Harnessing the Tet-Off system for effective gene silencing in <i>Magnaporthe oryzae</i>. [PDF]

Front Plant Sci
Fang Z, Yang F, Ma Y, Cai Y, Chen X, Yang S, Saddeeq AY, Wang Z, Naqvi NI, Zheng W.   +9 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Effective Gene Silencing in Plants by Synthetic Trans-Acting siRNAs Derived From Minimal Precursors. [PDF]

Bio Protoc
Cisneros AE, Alarcia A, Juárez-Molina M, Carbonell A.   +3 more
europepmc   +1 more source

On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing

Cell, 2001
T. Sijen, J. Fleenor, F. Simmer, K. Thijssen, S. Parrish, L. Timmons, R. Plasterk, A. Fire   +7 more
semanticscholar   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Using real-time qPCR to evaluate RNAi-mediated gene silencing [PDF]

, 2009
De Clercq, S, De Paepe, Anne, Marine, J C, Mestdagh, Pieter, Pattyn, Filip, Speleman, Franki, Van Maerken, Tom, Vandesompele, Jo, Yigit, Nurten   +8 more
core   +2 more sources

Gene silencing in plants by artificial small RNAs derived from minimal precursors and expressed via tobacco rattle virus. [PDF]

Plant Mol Biol
Juárez-Molina M, Alarcia A, Primc A, Ortega-Miralles I, Cisneros AE, Carbonell A.   +5 more
europepmc   +1 more source

In vitro RNA-mediated gene silencing of Fusarium oxysporum f.sp. cubense from Ecuador and assessment of RNAi molecule stability in banana plants [PDF]

Ricardo Pacheco, Julio Bonilla, Aracely Paguay, Freddy Magdama, Pablo Chong   +4 more
openalex   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

A dual-functional cobalt ferrite nanocomplex for targeted cisplatin prodrug delivery and MALAT1 gene silencing in gastric cancer cells. [PDF]

Sci Rep
Doryani F, Ahmadi A, Nikmanesh H, Azami F, Ghasemi A.   +4 more
europepmc   +1 more source