Results 261 to 270 of about 355,065 (295)
Correction to: Expanded CAG/CTG repeats resist gene silencing mediated by targeted epigenome editing. [PDF]
Hum Mol Geneteuropepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Current Opinion in Genetics & Development, 2000
About two years ago, it was recognized that introduction of double-stranded RNA (dsRNA) had a potent effect on gene expression, in particular on mRNA stability. Since then, this process has been found to occur in many different organisms, and to bear a strong resemblance to a previously recognized process in plants, called cosuppression.
René F. Ketting, Ronald H.A. Plasterk
openaire +3 more sources
About two years ago, it was recognized that introduction of double-stranded RNA (dsRNA) had a potent effect on gene expression, in particular on mRNA stability. Since then, this process has been found to occur in many different organisms, and to bear a strong resemblance to a previously recognized process in plants, called cosuppression.
René F. Ketting, Ronald H.A. Plasterk
openaire +3 more sources
Nature, 2002
The discovery that a transcriptional repressor is turned on in prostate tumours as they become metastatic, leading to the silencing of many genes, suggests a new mechanism for tumour progression.
Jacqueline Banyard, Bruce R. Zetter
openaire +2 more sources
The discovery that a transcriptional repressor is turned on in prostate tumours as they become metastatic, leading to the silencing of many genes, suggests a new mechanism for tumour progression.
Jacqueline Banyard, Bruce R. Zetter
openaire +2 more sources
2016
Silencing of cardiac genes by RNA interference (RNAi) has developed into a powerful new method to treat cardiac diseases. Small interfering (si)RNAs are the inducers of RNAi, but cultured primary cardiomyocytes and heart are highly resistant to siRNA transfection.
Wolfgang Poller +3 more
openaire +3 more sources
Silencing of cardiac genes by RNA interference (RNAi) has developed into a powerful new method to treat cardiac diseases. Small interfering (si)RNAs are the inducers of RNAi, but cultured primary cardiomyocytes and heart are highly resistant to siRNA transfection.
Wolfgang Poller +3 more
openaire +3 more sources
Cellular and Molecular Life Sciences, 2003
A number of gene-silencing phenomena including co-suppression discovered in plants, quelling in fungi and RNA interference in animals have been revealed to have steps in common. All occur in the cytoplasm at a post-transcriptional level with the mRNAs of target genes degraded in a sequence-specific manner. Small non-coding RNA molecules demonstrated to
A. S. Pickford, COGONI, Carlo
openaire +3 more sources
A number of gene-silencing phenomena including co-suppression discovered in plants, quelling in fungi and RNA interference in animals have been revealed to have steps in common. All occur in the cytoplasm at a post-transcriptional level with the mRNAs of target genes degraded in a sequence-specific manner. Small non-coding RNA molecules demonstrated to
A. S. Pickford, COGONI, Carlo
openaire +3 more sources
Transcriptional gene silencing mutants
2000Genetic approaches to identify molecular components of transcriptional gene silencing (TGS) in plants have yielded several Arabidopsis thaliana mutants and identified the first genes involved. All mutations found affect the maintenance of silencing and reactivate silent genes in trans.
Mittelsten Scheid, O., Paszkowski, Jerzy
openaire +4 more sources
2002
Gene silencing has evolved in a broad range of organisms probably as defense mechanisms against invasive nucleic acids. Two major strategies are utilized. Transcriptional gene silencing (TGS) acts to prevent RNA synthesis and posttranscriptional gene silencing (PTGS) acts to degrade existing RNA.
openaire +2 more sources
Gene silencing has evolved in a broad range of organisms probably as defense mechanisms against invasive nucleic acids. Two major strategies are utilized. Transcriptional gene silencing (TGS) acts to prevent RNA synthesis and posttranscriptional gene silencing (PTGS) acts to degrade existing RNA.
openaire +2 more sources
1995
“After such a survey one could readily come to the conclusion that the basis of the phenomenon is much too complex for profitable continuation of its investigation at this time”. [W.K. Baker (1968), in a review entitled “Position-effect variegation.”]
openaire +3 more sources
“After such a survey one could readily come to the conclusion that the basis of the phenomenon is much too complex for profitable continuation of its investigation at this time”. [W.K. Baker (1968), in a review entitled “Position-effect variegation.”]
openaire +3 more sources