Results 271 to 280 of about 7,203,409 (405)
Cas11 augments Cascade functions in type I-E CRISPR system but is redundant for gene silencing and plasmid interference. [PDF]
Biochem JPandey N, Misra CS, Rath D.
europepmc +1 more source
On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing
Cell, 2001 T. Sijen +7 more
semanticscholar +1 more source
The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication
Advanced Science, EarlyView.Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li +9 more
wiley +1 more source
An all-in-one plant virus-based vector toolkit for streamlined gene silencing, overexpression, and genome editing. [PDF]
Plant CommunHao Y +9 more
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miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay
Science, 2012 Sergej Djuranovic, A. Nahvi, R. Green
semanticscholar +1 more source
Advanced Science, EarlyView.Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li +24 more
wiley +1 more source
Spray-induced gene silencing for crop protection: recent advances and emerging trends. [PDF]
Front Plant SciChen C, Imran M, Feng X, Shen X, Sun Z.
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Position-effect variegation, heterochromatin formation, and gene silencing in Drosophila.
Cold Spring Harbor Perspectives in Biology, 2013 S. Elgin, G. Reuter
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