Results 291 to 300 of about 7,203,409 (405)

The impact of spray-induced gene silencing on cereal phyllosphere microbiota. [PDF]

Environ Microbiome
Sundararajan P, Ghosh S, Kelbessa BG, Whisson SC, Dubey M, Chawade A, Vetukuri RR.   +6 more
europepmc   +1 more source

Single‐Cell Transcriptomics Unravels Growth Factor Erv1‐Like Mediated Ferroptosis as a Key Driver of Intestinal Epithelial Dysfunction in Ulcerative Colitis

Advanced Science, EarlyView.
Single‐cell transcriptomic profiling of ulcerative colitis (UC) tissues identified downregulation of GFER in intestinal epithelial cells. Mechanistically, GFER interacts with PCBP1 to help maintain intracellular iron homeostasis and may also reduce lipid peroxidation by activating the PGC‐1α/PPARγ signaling pathway, thereby inhibiting ferroptosis ...
Ya Song, Fangyan Tan, Qian Song, Xiaohui Liao, Zhechuan Mei, Lin Lv   +5 more
wiley   +1 more source

Therapeutic Approaches of Viral Gene Silencing by Small Interfering RNA: Strategies to Prevent the Emergence of Antiviral Resistant Escape Mutants. [PDF]

Pharmaceuticals (Basel)
Kang H, Ga YJ, Kim JW, Kim C, Son SH, Gwak C, Yeh JY.   +6 more
europepmc   +1 more source

The E-cadherin gene is silenced by CpG methylation in human oral squamous cell carcinomas

, 2001
Shuko Nakayama, Akira Sasaki, Hiroshi Mese, Rafael E. Alcalde, Takanori Tsuji, Tomohiro Matsumura   +5 more
openalex   +1 more source

TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer

Advanced Science, EarlyView.
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, Amir Fardin, Gaelle Boncompain, Franck Perez, Federico Bussolino, Alessandro Cuomo, Sara Sigismund, Letizia Lanzetti   +16 more
wiley   +1 more source

Correction to 'Cytoplasmic and nuclear quality control and turnover of single-stranded RNA modulate post-transcriptional gene silencing in plants'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

Vesicular and non-vesicular extracellular small RNAs direct gene silencing in a plant-interacting bacterium. [PDF]

Nat Commun
Ravet A, Zervudacki J, Singla-Rastogi M, Charvin M, Thiebeauld O, Perez-Quintero AL, Courgeon L, Candat A, Lebeau L, Fortunato AE, Mendu V, Navarro L.   +11 more
europepmc   +1 more source

Characteristics of post‐transcriptional gene silencing

, 2001
Agustin Chicas, Giuseppe Macino
openalex   +2 more sources

Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis

Advanced Science, EarlyView.
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan, Han Ma, Jespar Chen, Gaifeng Ma, Alok Jha, Sipin Tan, Yaxi Zhu, Meidong Liu, Ke Liu, Xianzhong Xiao, Monowar Aziz, Huan Chen, Ping Wang, Huali Zhang   +13 more
wiley   +1 more source

The Ser7 phosphorylation of RNA polymerase II-CTD is required for the recruitment of E3 ubiquitin ligase Asr1 and subtelomeric gene silencing. [PDF]

J Biol Chem
Sudarshan N, Asalam M, Kumar A, Singh N, Gupta A, De I, Singh SK, Zhang KY, Akhtar MS.   +8 more
europepmc   +1 more source