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Virus-Induced Gene Silencing

2003
In the postgenomic era, large-scale functional genomic approaches are necessary for converting sequence information into functional information. A para-genetic approach, called virus-induced gene silencing (VIGS), offers a rapid means of gaining insight into gene function in plants.
S P, Dinesh-Kumar   +4 more
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Polycomb group gene silencing

Science, 2017
Gene Regulation Histone proteins wrap around DNA to form nucleosomes that package metazoan DNA into the nucleus. Chromatin compaction is also believed to be critical for the repression of homeotic genes by the Polycomb repressive complex 1 (PRC1) during development. Lau et al.
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RNA-triggered gene silencing

Trends in Genetics, 1999
Double-stranded RNA (dsRNA) has recently been shown to trigger sequence-specific gene silencing in a wide variety of organisms, including nematodes, plants, trypanosomes, fruit flies and planaria; meanwhile an as yet uncharacterized RNA trigger has been shown to induce DNA methylation in several different plant systems.
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Gene Silencing in Drosophila

1995
“After such a survey one could readily come to the conclusion that the basis of the phenomenon is much too complex for profitable continuation of its investigation at this time”. [W.K. Baker (1968), in a review entitled “Position-effect variegation.”]
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Posttranscriptional Gene Silencing

2009
Regenerative medicine is an emerging field that has been extensively studied and includes modern approaches for gene targeting. Recent findings have highlighted the effectiveness of gene silencing in therapeutic settings [1–7]. The key therapeutic advantage of using RNA interference (RNAi) lies in an ability to downregulate the expression of an ...
Volker Ruppert   +3 more
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Gene-Silencing Pesticides

Chemical & Engineering News Archive, 2014
When farmers began seeing increased damage from the western corn rootworm a few years ago, they knew that the beetle was developing resistance to a widely used toxin produced by the bacterium Bacil...
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Plant Gene Silencing

2000
Preface. 1. Paramutation in maize V.L. Chandler, et al. 2. Genomic imprinting in plants - observations and evolutionary implications M. Alleman, J. Doctor. 3. Nucleolar Dominance: uniparental gene silencing on a multi-megabase scale in genetic hybrids G. Pikaard. 4. Epigenetic aspects of somaclonal variation in plants S.M. Kaeppler, et al. 5. Plant DNA
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