Results 151 to 160 of about 1,756,365 (358)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Automated design of hammerhead ribozymes and validation by targeting the PABPN1 gene transcript [PDF]

, 2015
Nawwaf Kharma, Luc Varin, Aida Abu‐Baker, Jonathan Ouellet, Sabrine Najeh, Mohammad-Reza Ehdaeivand, Gabriel Belmonte, Anas Ambri, Guy A. Rouleau, Jonathan Perreault   +9 more
openalex   +1 more source

Analyzing the Expression of MicroRNA-375 and its Target Gene p53 in Oral Squamous Cell Carcinoma and its Implication in Oral Carcinogenesis

, 2023
Sangeetha Narasimhan, Malathi Narasimhan, Shishir Shetty, Sharada T Rajan, Sausan Al Kawas, Vijaya Nirmala Subramani   +5 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Multiple microRNAs regulate human FOXP2 gene expression by targeting sequences in its 3' untranslated region [PDF]

, 2014
Lijuan Fu, Zhimin Shi, Guan‐Zheng Luo, Weihong Tu, XiuJie Wang, Zhide Fang, XiaoChing Li   +6 more
openalex   +1 more source

Targeted Down Regulation Of Core Mitochondrial Genes During SARS-CoV-2 Infection [PDF]

, 2022
Joseph W. Guarnieri, Joseph M. Dybas, Hossein Fazelinia, Man S. Kim, Justin J. Frere, Yuanchao Zhang, Yentli E. Soto Albrecht, Deborah G. Murdock, Alessia Angelin, Larry N. Singh, Scott L. Weiss, Sonja M. Best, Marie T. Lott, Henry Cope, Victoria Zaksas, Amanda Saravia-Butler, Cem Meydan, Jonathan Foox, Christopher Mozsary, Yared H. Kidane, Waldemar Priebe, Mark R. Emmett, Robert Meller, Urminder Singh, Yaron Bram, Benjamin R. tenOever, Mark T. Heise, Nathaniel J. Moorman, Emily A. Madden, Sharon Taft-Benz, Elizabeth J. Anderson, Wes Sanders, Rebekah J. Dickmander, Victoria K. Baxter, Stephen B. Baylin, Eve Syrkin Wurtele, Pedro M. Moraes‐Vieira, Deanne Taylor, Christopher E. Mason, Jonathan C. Schisler, Robert E. Schwartz, Afshin Beheshti, Douglas C. Wallace   +42 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Gene Targeting [PDF]

Cell, 2004
Vanhaesebroeck, Bart, Rohn, Jennifer L., Waterfield, Michael D.   +2 more
openaire   +1 more source

Transgenic and gene-targeted mice as models for chronic obstructive pulmonary disease: Fig. 1— [PDF]

, 2007
SD Shapiro
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source