Results 271 to 280 of about 12,185,719 (426)

Gene targeting in polymerase theta-deficient Arabidopsis thaliana. [PDF]

Plant J, 2022
van Tol N, van Schendel R, Bos A, van Kregten M, de Pater S, Hooykaas PJJ, Tijsterman M.   +6 more
europepmc   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

A novel approach in using insect-based spinach-food waste for gene targeting to cancer tissues. [PDF]

Sci Rep
Majd-Marani S, Eftekhari A, Elias SG, Beffa R, Alebrahim MT, Mishra AP, Afrouz M.   +6 more
europepmc   +1 more source

Shortened CRISPR-Cas9 arrays enable multiplexed gene targeting in bacteria from a smaller DNA footprint. [PDF]

RNA Biol, 2023
Gawlitt S, Liao C, Achmedov T, Beisel CL.   +3 more
europepmc   +1 more source

Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development. [PDF]

, 1994
Lan S. Chen, Bruce Ostrow, Sherrie Tafuri, Rex L. Chisholm   +3 more
openalex   +1 more source

Targeted gene repair [PDF]

Gene Therapy, 1999
openaire   +3 more sources

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

Molecular Oncology, Volume 19, Issue 4, Page 1203-1228, April 2025.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso, Shivani Bailey, Luz Alonso‐Crisostomo, Dawn Ward, Christos Panayi, Zachary G. L. Scurlock, Harpreet K. Saini, Stephen P. Smith, James C. Nicholson, Anton J. Enright, Cinzia G. Scarpini, Nicholas Coleman, Matthew J. Murray   +12 more
wiley   +1 more source

Utilizing shRNA-expressing lentivectors for viral hemorrhagic septicemia virus suppression via NV gene targeting. [PDF]

Front Vet Sci
Pourhoseini Dehkordi N, Saffar B, Mokhtari A, Asadi Samani L, Amini A.   +4 more
europepmc   +1 more source

Gene targeting in amyotrophic lateral sclerosis using causality-based feature selection and machine learning. [PDF]

Mol Med, 2023
Founta K, Dafou D, Kanata E, Sklaviadis T, Zanos TP, Gounaris A, Xanthopoulos K.   +6 more
europepmc   +1 more source

A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency

, 1992
Thomas M. Magin, Jim McWhir, David W. Melton   +2 more
openalex   +1 more source