Results 291 to 300 of about 12,501,640 (402)

The (6;9) Chromosome Translocation, Associated with a Specific Subtype of Acute Nonlymphocytic Leukemia, Leads to Aberrant Transcription of a Target Gene on 9q34 [PDF]

, 1990
Marieke von Lindern, Annemarie Poustka, Hans Lerach, Gerard C. Grosveld   +3 more
openalex   +1 more source

Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila

Genetics, 2013
S. Kondo, R. Ueda
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Non-electrophilic NRF2 activators promote wound healing in human keratinocytes and diabetic mice and demonstrate selective downstream gene targeting. [PDF]

Sci Rep
Barakat M, Han C, Chen L, David BP, Shi J, Xu A, Skowron KJ, Johnson T, Woods RA, Ankireddy A, Reddy SP, Moore TW, DiPietro LA.   +12 more
europepmc   +1 more source

Targets of homeotic gene regulation in Drosophila [PDF]

, 1992
Robert A. H.White, Jenny J. Brookman, Alex P. Gould, Lisa Meadows, L. S. Shashidhara, David Strutt, T. A. Weaver   +6 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Gene targeting in adult organs using in vivo cleavable donor plasmids for CRISPR-Cas9 and CRISPR-Cas12a. [PDF]

Sci Rep
Ishibashi R, Maki R, Toyoshima F.
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Simple promotion of Cas9 and Cas12a expression improves gene targeting via an all-in-one strategy. [PDF]

Front Plant Sci
Cheng Y, Zhang L, Li J, Dang X, Zhu JK, Shimada H, Miki D.   +6 more
europepmc   +1 more source

Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice.

, 1994
O. Smithies, H. S. Kim
openalex   +2 more sources