Results 31 to 40 of about 4,645,161 (307)

Hypoxia-Inducible Factor-1α (HIF-1α) Potentiates β-Cell Survival after Islet Transplantation of Human and Mouse Islets

open access: yesCell Transplantation, 2013
A high proportion of β-cells die within days of islet transplantation. Reports suggest that induction of hypoxia-inducible factor-1α (HIF-1α) predicts adverse transplant outcomes.
Rebecca A. Stokes   +12 more
doaj   +1 more source

Influence of BmNPV orf98 on DNA replication, transcription and virus package of Bombyx mori nucleopolyhedrovirus

open access: yes浙江大学学报. 农业与生命科学版, 2015
Baculoviruses have been considered as the powerful vectors to express the exogenous gene. And the representative vectors in baculovirus expression vector system is Autographa californica multinucleocapsid nucleopolyhedrovirus (AcMNPV) and Bombyx mori ...
Shi Lili   +6 more
doaj   +1 more source

Microplastics as Vehicles of Environmental PAHs to Marine Organisms: Combined Chemical and Physical Hazards to the Mediterranean Mussels, Mytilus galloprovincialis

open access: yesFrontiers in Marine Science, 2018
The ubiquitous occurrence of microplastics (MPs) in the marine environment is raising concern for interactions with marine organisms. These particles efficiently adsorb persistent organic pollutants from surrounding environment and, due to the small size,
Lucia Pittura   +9 more
doaj   +1 more source

Control of Globin Gene Transcription [PDF]

open access: yesAnnual Review of Cell Biology, 1990
n ...
Evans, Todd   +2 more
openaire   +3 more sources

Dynamic DNA methylation in the brain: a new epigenetic mark for experience-dependent plasticity.

open access: yesFrontiers in Cellular Neuroscience, 2015
Experience-dependent plasticity is the ability of brain circuits to undergo molecular, structural and functional changes as a function of neural activity.
Paola eTognini   +3 more
doaj   +1 more source

OTUD7B Deubiquitinates LSD1 to Govern Its Binding Partner Specificity, Homeostasis, and Breast Cancer Metastasis

open access: yesAdvanced Science, 2021
Genomic amplification of OTUD7B is frequently found across human cancers. But its role in tumorigenesis is poorly understood. Lysine‐specific demethylase 1 (LSD1) is known to execute epigenetic regulation by forming corepressor complex with CoREST ...
Zhicheng Gong   +13 more
doaj   +1 more source

An Introduction to Transcription and Gene Regulation [PDF]

open access: yesJournal of Biological Chemistry, 2010
Having been offered the opportunity to contribute one of the episodes of this series of personal history accounts, I have chosen to write about circumstances that led me to the start of the scientific path that I have followed for the past forty odd years.
openaire   +2 more sources

Transcriptional gene silencing in humans [PDF]

open access: yesNucleic Acids Research, 2016
It has been over a decade since the first observation that small non-coding RNAs can functionally modulate epigenetic states in human cells to achieve functional transcriptional gene silencing (TGS). TGS is mechanistically distinct from the RNA interference (RNAi) gene-silencing pathway.
Weinberg, Marc S, Morris, Kevin V
openaire   +3 more sources

A local regulatory network around three NAC transcription factors in stress responses and senescence in Arabidopsis leaves [PDF]

open access: yes, 2013
A model is presented describing the gene regulatory network surrounding three similar NAC transcription factors that have roles in Arabidopsis leaf senescence and stress responses. ANAC019, ANAC055 and ANAC072 belong to the same clade of NAC domain genes
Cooke, Emma J.   +31 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy