Expression of the plasma prekallikrein gene: utilization of multiple transcription start sites and alternative promoter regions [PDF]
, 2005 The plasma prekallikrein gene is expressed in many different human tissues at distinctly different levels and therefore tissue-specific control of the gene transcription is likely.
Sidarovich, Viktoryia +4 more
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A dynamical model reveals gene co-localizations in nucleus [PDF]
, 2011 Co-localization of networks of genes in the nucleus is thought to play an important role in determining gene expression patterns. Based upon experimental data, we built a dynamical model to test whether pure diffusion could account for the observed co ...
Peter Fraser +27 more
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Identification and validation of transcription factors that regulate chromatin dynamics [PDF]
, 2012 Gene expression has to be tightly regulated during all cellular processes. During embryonic development differentiating cells loose their developmental potential and acquire specific functions by activating lineage-specific genes.
Schöler, Anne
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The Nuclear Lamina as an Organizer of Chromosome Architecture
Cells, 2019 The nuclear lamina (NL) is a meshwork of lamins and lamin-associated proteins adjoining the inner side of the nuclear envelope. In early embryonic cells, the NL mainly suppresses background transcription, whereas, in differentiated cell types, its ...
Yuri Y. Shevelyov, Sergey V. Ulianov
doaj +1 more source
Methylation hallmarks on the histone tail as a linker of osmotic stress and gene transcription
Frontiers in Plant Science, 2022 Plants dynamically manipulate their gene expression in acclimation to the challenging environment. Hereinto, the histone methylation tunes the gene transcription via modulation of the chromatin accessibility to transcription machinery.
Mu Xiao, Jinbiao Wang, Fang Xu
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Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms [PDF]
, 2009 Baumbach J, Rahmann S, Tauch A. Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms. BMC Systems Biology.
Sven Rahmann +5 more
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Statistical reconstruction of transcription factor activity using Michaelis-Menten kinetics [PDF]
, 2007 Summary. The basic building block of a gene regulatory network consists of a gene encoding a transcription factor (TF) and the gene(s) it regulates. Considerable efforts have been directed recently at devising experiments and algorithms to determine TFs
Smith, C.P., +16 more
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Scientific Reports, 2017 The PBAF chromatin-remodeling complexes are multi-protein machines, regulating expression of genes involved in proliferation and differentiation. PHF10 is a subunit of the PBAF essential for its association with chromatin. Mammalian PHF10 is expressed as
Victor V. Tatarskiy +5 more
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Frontiers in Immunology, 2019 Beside its classical role as a serum effector system of innate immunity, evidence is accumulating that complement has an intracellular repertoire of components that provides not only immune defense, but also functions to maintain cellular homeostasis ...
Mariann Kremlitzka +5 more
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A Novel Strategy for Regulating mRNA’s Degradation via Interfering the AUF1’s Binding to mRNA
Molecules, 2022 The study on the mechanism and kinetics of mRNA degradation provides a new vision for chemical intervention on protein expression. The AU enrichment element (ARE) in mRNA 3′-UTR can be recognized and bound by the ARE binding protein (AU-rich Element ...
Kun-Tao Li +3 more
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