Results 211 to 220 of about 1,319,898 (363)

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

The Catholic Theology Of Genetic Manipulation [PDF]

, 2004
Pace, Andrew
core   +2 more sources

Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain

Science Translational Medicine, 2013
E. Hudry, Jonathan Dashkoff, Alysson D. Roe, S. Takeda, Robert M. Koffie, T. Hashimoto, M. Scheel, T. Spires-Jones, Michal Arbel-Ornath, R. Betensky, B. Davidson, B. Hyman   +11 more
semanticscholar   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Contiguous and complete assemblies of <i>Blastocystis</i> gut microbiome-associated protists reveal evolutionary diversification to host ecology. [PDF]

Genome Res
Lind AL, McDonald NA, Gerrick ER, Bhatt AS, Pollard KS.   +4 more
europepmc   +1 more source

Receptor-mediated gene delivery employing lectin-binding specificity [PDF]

, 1994
Batra, R. K., Curiel, David T., Garver, R. I., Wagner, Ernst, Wang-Johanning, F.   +4 more
core  

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Protoplast-Based Regeneration Enables CRISPR/Cas9 Application in Two Temperate <i>Japonica</i> Rice Cultivars. [PDF]

Plants (Basel)
Barrera M, Olmedo B, Narváez M, Moenne-Locoz F, Rubio A, Pérez C, Cordero-Lara K, Prieto H.   +7 more
europepmc   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Nanoneedle-Based Transdermal Gene Delivery: A Minimally Invasive Strategy for Gene Therapy. [PDF]

Int J Mol Sci
Akbuğa FJ, Arpa MD, Şalva E.
europepmc   +1 more source