Results 231 to 240 of about 621,194 (302)

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

Exploring Deleterious Nonsynonymous SNPs in the <i>ACADM</i> Gene: Insights Into Medium-Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) via In Silico Analysis. [PDF]

Genet Res (Camb)
Iqbal MW, Shahab M, Dabiellil F, Bin Jardan YA, Bourhia M, Sun X, Yuan Q.   +6 more
europepmc   +1 more source

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

Advanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter, Shashwat S. Agarwal, Joseph W. Tinapple, Joseph M. Barlage, Travis H. Jones, Jonathan W. Song   +5 more
wiley   +1 more source

Investigating Outcomes of Gamete Donation in Assisted Reproductive Technology: A Retrospective Study. [PDF]

JBRA Assist Reprod
Soares S, Leal C, Barreiro M, Vale-Fernandes E.   +3 more
europepmc   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

scSpecies: enhancement of network architecture alignment in comparative single-cell studies. [PDF]

Genome Biol
Schächter C, Hackenberg M, Treppner M, Raum H, Bödecker J, Binder H.   +5 more
europepmc   +1 more source

Transfer learning models for bacterial strain dissemination biomarkers using weighted non-parallel proximal support vector machines. [PDF]

BMC Bioinformatics
Ugwu UO, Slayden RA, Kirby M.
europepmc   +1 more source

Emerging trends in genome editing of wild animals. [PDF]

Transgenic Res
Blix T, Myhr AI.
europepmc   +1 more source

Advances in detecting category A biothreat agents: Toward symptom-driven sensing strategies. [PDF]

Synth Syst Biotechnol
Li R, Zhang Y, Fu Q, Zhao C, Ren S, Zhong R, Bai S.   +6 more
europepmc   +1 more source