Are General anesthetics neurotoxic?
Introduction: General anaesthesia has been used worldwide since its first public demonstration with ether in 1846. Until a little more than a decade ago, it was believed that the anaesthetic state was limited to the period of exposure. Studies in rats, pigs, and rhesus monkeys have shown that almost all general anaesthetics accelerate the apoptotic ...
Breno Souza Benevides+9 more
openaire +2 more sources
Comparison of Anesthesia for Dental/Oral Surgery by Office-based Dentist Anesthesiologists versus Operating Room-based Physician Anesthesiologists [PDF]
Few studies have examined the practice characteristics of dentist anesthesiologists and compared them to other anesthesia providers. Using outcomes from the National Anesthesia Clinical Outcomes Registry and the Society for Ambulatory Anesthesia Clinical
Gabriel, Rodney A.+4 more
core +1 more source
Objective The study objective was to estimate the budget impact of funding a standardized education and exercise therapy program, Good Life with osteoArthritis in Denmark (GLA:D) for people with hip and knee osteoarthritis (OA) waiting for total joint replacement (TJR) consultation in a universal publicly insured health care system in Canada.
Darren R. Mazzei+4 more
wiley +1 more source
Qualitative and Quantitative Characteristics of the Electroencephalogram in Normal Horses during Administration of Inhaled Anesthesia. [PDF]
BackgroundThe effects of anesthesia on the equine electroencephalogram (EEG) after administration of various drugs for sedation, induction, and maintenance are known, but not that the effect of inhaled anesthetics alone for EEG recording.ObjectiveTo ...
Aleman, M+8 more
core +1 more source
Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation
Objective Gout flares are the most important clinical feature of the disease. A hypothetical maximum flare occurrence in the preceding six months has been suggested to be no flares for a patient‐acceptable symptom state (PASS) and only one flare for low disease activity (LDA).
Lisa K. Stamp+6 more
wiley +1 more source
Scientometrics of anesthetic drugs and their techniques of administration, 1984–2013 [PDF]
The aim of this study was to assess progress in the field of anesthetic drugs over the past 30 years using scientometric indices: popularity indices (general and specific), representing the proportion of articles on a drug relative to all articles in the
Kissin, Igor, Vlassakov, Kamen V
core +1 more source
Objective This study aimed to identify the top 10 international research priorities for musculoskeletal health of people with generalized joint hypermobility. Methods A three‐round Delphi method using an online survey was implemented. Three participant stakeholder groups were eligible for inclusion: (1) people with lived experience of joint ...
Sara Habibian+4 more
wiley +1 more source
HYPOXIC BRAIN INJURY IN THE EARLY POSTOPERATIVE PERIOD (A CASE REPORT)
The neurotoxicity of general anesthetic drugs still appears as a relevant interdisciplinary problem. All general anesthetics that are currently in use exhibit a neurotoxic effect on the brain at all stages of its development. It is impossible to evaluate
A. M. Ovezov+6 more
doaj +1 more source
Mechanism of Anesthetic Action: Oxygen Pathway Perturbation Hypothesis [PDF]
Although more than 150 years have past since the discovery of general anesthetics, how they precisely work remains a mystery. We propose a novel unitary mechanism of general anesthesia verifiable by experiments. In the proposed mechanism, general anesthetics perturb oxygen pathways in both membranes and oxygen-utilizing proteins such that the ...
arxiv
Anesthesia in the surgery of strabismus: role of anesthetic agents in the ocular deviation and surgical outcome [PDF]
Purpose: To determine whether the changes in the ocular alignment following general anesthesia, maintained with two different inhalational anesthetic agents, sevoflurane and desflurane, can be used as a predictor for surgical outcomes in children with ...
Arrico, Loredana+5 more
core +1 more source