Objectives This study aimed to investigate hand function trajectories over 5 years in primary hand osteoarthritis. Additionally, determinants of baseline and longitudinal hand function were assessed. Methods 538 patients with both baseline and 5‐year study visits were analyzed.
Annemiek V.E.M. Olde Meule +4 more
wiley +1 more source
The effect of general anesthetics on neutrophil-like differentiated HL60 cells: sevoflurane activates the mitochondrial function to promote their bactericidal action. [PDF]
Asei K +5 more
europepmc +1 more source
Associations of Rheumatoid Arthritis Disease Activity with Frailty Over Five Years of Follow‐up
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis registry enrolled from 2003 to 2022 were included. The exposure was RA disease activity measured by Disease Activity Score in 28‐joints (DAS28)
Courtney N. Loecker +14 more
wiley +1 more source
Novel Spiro-Barbiturates Can Reverse the Action of General Anesthetics on the GABA<sub>A</sub>R. [PDF]
Koinas D +4 more
europepmc +1 more source
General Anesthetics on Immune System Cytokines: A Narrative Review Article. [PDF]
Jafarzadeh A +4 more
europepmc +1 more source
Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni +7 more
wiley +1 more source
Cannabinoids and General Anesthetics: Revisiting Molecular Mechanisms of Their Pharmacological Interactions. [PDF]
Echeverria-Villalobos M +6 more
europepmc +1 more source
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan +10 more
wiley +1 more source
In vivo assessment of the influence of general anesthetics on transmembrane water cycling in the brain. [PDF]
Cavallari E +6 more
europepmc +1 more source
General anesthetics activate a potent central pain-suppression circuit in the amygdala. [PDF]
Hua T +10 more
europepmc +1 more source

