Results 11 to 20 of about 78,545 (352)
Effect of general anesthetics on the developing brain
Journal of Anaesthesiology Clinical Pharmacology, 2012 Studies on rodents and subhuman primates suggest that prolonged exposure to general anesthetics may induce widespread neuronal cell death and neurological sequelae; seriously questioning the safety of pediatric anesthesia.
S Velayudha Reddy
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Neural Regeneration Research, 2017 Postoperative cognitive dysfunction (POCD) is a multifactorial process with a huge number of predisposing, causal, and precipitating factors. In this scenario, the neuroinflammation and the microglial activation play a pivotal role by triggering and ...
Marco Cascella, Sabrina Bimonte
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THE ASSAY OF GENERAL ANESTHETIC AGENTS
Annals of Surgery, 1939 Henry K. Beecher
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Molecular mechanisms of general anesthesia [PDF]
Korean Journal of Anesthesiology, 2010 General anesthetics produce a widespread neurodepression in the central nervous system by enhancing inhibitory neurotransmission and reducing excitatory neurotransmission.
Yong Son
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General Anesthetics Commonly Used for Laboratory Animals
Shiyan dongwu yu bijiao yixue, 2022 General anesthetics used for laboratory animals are mostly controlled drugs, and are subject to strict supervision by the competent government agency in China.
LU Xiao +5 more
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Are Local Anesthetics and General Anesthetics Different? [PDF]
Biophysical Journal, 2014 It is widely believed that general and local anesthetics act by different mechanisms. While there is general agreement that the mode of action of general anesthetics is poorly understood, local anesthetics are believed to block voltage-gated sodium channels and thereby affect action potentials in nerves.
Sasse-Middelhoff, Henrike +2 more
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Structural interplay of anesthetics and paralytics on muscle nicotinic receptors
Nature Communications, 2023 General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami +3 more
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The impact of preoperative glycated hemoglobin (HbA1c) on postoperative complications after elective major abdominal surgery: a meta-analysis [PDF]
Korean Journal of Anesthesiology, 2022 Background Diabetes is a risk factor for postoperative complications. Previous meta-analyses have shown that elevated glycated hemoglobin (HbA1c) levels are associated with postoperative complications in various surgical populations. However, this is the
Joanna K. L. Wong +5 more
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The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]
Korean Journal of Anesthesiology, 2014 BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee +6 more
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BMC Anesthesiology, 2021 Background Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics on spontaneous respiration in non-
Xuechao Hao +3 more
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