Results 11 to 20 of about 80,551 (349)

The role of general anesthetics and the mechanisms of hippocampal and extra-hippocampal dysfunctions in the genesis of postoperative cognitive dysfunction

Neural Regeneration Research, 2017
Postoperative cognitive dysfunction (POCD) is a multifactorial process with a huge number of predisposing, causal, and precipitating factors. In this scenario, the neuroinflammation and the microglial activation play a pivotal role by triggering and ...
Marco Cascella, Sabrina Bimonte
doaj   +2 more sources

Retracted: Relationship between Artificial Intelligence-Based General Anesthetics and Postoperative Cognitive Dysfunction. [PDF]

J Healthc Eng, 2022
Healthcare Engineering JO.
europepmc   +3 more sources

General Anesthetics Commonly Used for Laboratory Animals

Shiyan dongwu yu bijiao yixue, 2022
General anesthetics used for laboratory animals are mostly controlled drugs, and are subject to strict supervision by the competent government agency in China.
LU Xiao, YU Lingzhi, CHOU Sonja Tsung-Ying, LI Ruying, CHEN Wenjun, JIANG Shanxiang   +5 more
doaj   +1 more source

Structural interplay of anesthetics and paralytics on muscle nicotinic receptors

Nature Communications, 2023
General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami, Md Mahfuzur Rahman, Jinfeng Teng, Ryan E. Hibbs   +3 more
doaj   +1 more source

The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]

Korean Journal of Anesthesiology, 2014
BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee, Yong-Hee Park, Hyun-Gul Song, Hee-Pyoung Park, Hee-Soo Kim, Chong-Sung Kim, Jin-Tae Kim   +6 more
doaj   +1 more source

Anesthetic spindles serve as EEG markers of the depth variations in anesthesia induced by multifarious general anesthetics in mouse experiments. [PDF]

Front Pharmacol
You Y, Liu H, Yang Z, Chen Y, Yang F, Yu T, Zhang Y.   +6 more
europepmc   +3 more sources

Volatile anesthetics maintain tidal volume and minute ventilation to a greater degree than propofol under spontaneous respiration

BMC Anesthesiology, 2021
Background Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics on spontaneous respiration in non-
Xuechao Hao, Mengchan Ou, Yu Li, Cheng Zhou   +3 more
doaj   +1 more source

Volatile Anesthetics Regulate Anti-Cancer Relevant Signaling

Frontiers in Oncology, 2021
Volatile anesthetics are widely used inhalation anesthetics in clinical anesthesia. In recent years, the regulation of anti-cancer relevant signaling of volatile anesthetics has drawn the attention of investigators.
Jiaqiang Wang, Chien-shan Cheng, Chien-shan Cheng, Yan Lu, Shen Sun, Shaoqiang Huang   +5 more
doaj   +1 more source

New patents on topical anesthetics. [PDF]

, 2014
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano, CANTISANI, CARMEN, D'ANDREA, Vito, Frascani, F, MACALUSO, LAURA, paolino, giovanni, RICHETTA, Antonio Giovanni   +6 more
core   +1 more source

Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]

, 2015
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR, Brosnan, RJ, Fletcher, DJ, Holliday, TA, Kass, PH, LeCouteur, RA, Steffey, EP, Tharp, B, Williams, DC   +8 more
core   +1 more source