Results 11 to 20 of about 77,182 (352)

Effect of general anesthetics on the developing brain

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2012
Studies on rodents and subhuman primates suggest that prolonged exposure to general anesthetics may induce widespread neuronal cell death and neurological sequelae; seriously questioning the safety of pediatric anesthesia.
S Velayudha Reddy
doaj   +4 more sources

ETHYL CHLORID AS A GENERAL ANESTHETIC. [PDF]

open access: greenJAMA: The Journal of the American Medical Association, 1906
I have lately noticed inThe Journalvarious articles on the use of ethyl chlorid as a short general anesthetic, and some specially constructed masks. To my mind the latter are too expensive for the general practitioner, and I desire to present a method that I use in the receiving ward of the Cincinnati Hospital.
A. E. OSMOND
openalex   +4 more sources

Molecular mechanisms of general anesthesia [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
General anesthetics produce a widespread neurodepression in the central nervous system by enhancing inhibitory neurotransmission and reducing excitatory neurotransmission.
Yong Son
doaj   +1 more source

Are Local Anesthetics and General Anesthetics Different? [PDF]

open access: yesBiophysical Journal, 2014
It is widely believed that general and local anesthetics act by different mechanisms. While there is general agreement that the mode of action of general anesthetics is poorly understood, local anesthetics are believed to block voltage-gated sodium channels and thereby affect action potentials in nerves.
Sasse-Middelhoff, Henrike   +2 more
openaire   +2 more sources

General Anesthetics Commonly Used for Laboratory Animals

open access: yesShiyan dongwu yu bijiao yixue, 2022
General anesthetics used for laboratory animals are mostly controlled drugs, and are subject to strict supervision by the competent government agency in China.
LU Xiao   +5 more
doaj   +1 more source

Structural interplay of anesthetics and paralytics on muscle nicotinic receptors

open access: yesNature Communications, 2023
General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami   +3 more
doaj   +1 more source

The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]

open access: yesKorean Journal of Anesthesiology, 2014
BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee   +6 more
doaj   +1 more source

Volatile anesthetics maintain tidal volume and minute ventilation to a greater degree than propofol under spontaneous respiration

open access: yesBMC Anesthesiology, 2021
Background Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics on spontaneous respiration in non-
Xuechao Hao   +3 more
doaj   +1 more source

The Effects of General Anesthetics on Synaptic Transmission. [PDF]

open access: yesCurr Neuropharmacol, 2020
General anesthetics are a class of drugs that target the central nervous system and are widely used for various medical procedures. General anesthetics produce many behavioral changes required for clinical intervention, including amnesia, hypnosis, analgesia, and immobility; while they may also induce side effects like respiration and cardiovascular ...
Hao X   +9 more
europepmc   +5 more sources

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