Characterization of Large-Scale Functional Brain Networks During Ketamine-Medetomidine Anesthetic Induction [PDF]
arXiv, 2016 Several experiments provide evidence that specialized brain regions functionally interact and reveal that the brain processes and integrates information in a specific and structured manner. Networks can be applied to model brain functional activities, providing means to characterize and quantify this structured form of organization.
Padovani, Eduardo C.
arxiv +2 more sources
Effect of general anesthetics on the developing brain
Journal of Anaesthesiology Clinical Pharmacology, 2012 Studies on rodents and subhuman primates suggest that prolonged exposure to general anesthetics may induce widespread neuronal cell death and neurological sequelae; seriously questioning the safety of pediatric anesthesia.
S Velayudha Reddy
doaj +4 more sources
Characterization of the Community Structure of Large-Scale Functional Brain Networks During Ketamine-Medetomidine Anesthetic Induction [PDF]
arXiv, 2016 One of the main goals of neuroscience is to understand how an organism's cognitive capacities or physiological states are potentially related to brain activities that involve the interaction of multiple brain structures and cortical areas. A key feature of functional brain networks is that they are modularly structured, and this modular architecture is
Padovani, Eduardo C.
arxiv +2 more sources
General anesthetics inhibit LPS-induced IL-1β expression in glial cells. [PDF]
PLoS ONE, 2013 BACKGROUND: Glial cells, including microglia and astrocytes, are considered the primary source of proinflammatory cytokines in the brain. Immune insults stimulate glial cells to secrete proinflammatory cytokines that modulate the acute systemic response,
Tomoharu Tanaka +5 more
doaj +2 more sources
A Common Neuroendocrine Substrate for Diverse General Anesthetics and Sleep. [PDF]
Neuron, 2019 Jiang-Xie LF +6 more
europepmc +2 more sources
Structure and Dynamics of Brain Lobe's Functional Networks at the Onset of Anesthesia-Induced Loss of Consciousness [PDF]
arXiv, 2016 Anesthetic agents are neurotropic drugs capable of inducing significant alterations in the thalamocortical system, promoting a profound decrease in awareness and level of consciousness. There is experimental evidence that general anesthesia affects large-scale functional networks, leading to alterations in the brain's state.
Padovani, Eduardo C.
arxiv +2 more sources
General Anesthetics and Neurotoxicity: How Much Do We Know? [PDF]
Anesthesiol Clin, 2016 Jevtovic-Todorovic V.
europepmc +2 more sources
Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties. [PDF]
Proc Natl Acad Sci U S A, 2017 Herold KF +4 more
europepmc +2 more sources
The impact of preoperative glycated hemoglobin (HbA1c) on postoperative complications after elective major abdominal surgery: a meta-analysis [PDF]
Korean Journal of Anesthesiology, 2022 Background Diabetes is a risk factor for postoperative complications. Previous meta-analyses have shown that elevated glycated hemoglobin (HbA1c) levels are associated with postoperative complications in various surgical populations. However, this is the
Joanna K. L. Wong +5 more
doaj +1 more source
Molecular mechanisms of general anesthesia [PDF]
Korean Journal of Anesthesiology, 2010 General anesthetics produce a widespread neurodepression in the central nervous system by enhancing inhibitory neurotransmission and reducing excitatory neurotransmission.
Yong Son
doaj +1 more source