Results 71 to 80 of about 1,179,697 (255)
Teaching GLM Concepts: Explicating the Connections
Journal of Methods and Measurement in the Social Sciences, 2015 The purpose of the present paper is to encourage textbook authors, quantitative instructors, curriculum writers, and software developers to move away from the use of isolated apparently disconnected analyses and instead move towards the use of the ...
Susan Troncoso Skidmore
doaj +1 more source
Effects of aging on brain networks during swallowing: general linear model and independent component analyses. [PDF]
Sci Rep, 2021 Tae WS, Lee S, Choi S, Pyun SB.
europepmc +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Flexible scan statistic with a restricted likelihood ratio for optimized COVID-19 surveillance
Geospatial HealthDisease surveillance remains important for early detection of new COVID-19 variants. For this purpose, the World Health Organization (WHO) recommends integrating of COVID-19 surveillance with other respiratory diseases.
Ernest Akyereko +3 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
One missing value problem in Latin square design of any order: Exact analysis of variance
Cogent Engineering, 2017 This research proposes a simplified exact approach based on the general linear model for solving the K × K Latin square design (LSD) with one replicate and one missing value, given the lack of ready-made mathematical formulas for the sub-variance.
Kittiwat Sirikasemsuk +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Predicting the Aqueductal Cerebrospinal Fluid Pulse: A Statistical Approach
Applied Sciences, 2019 The cerebrospinal fluid (CSF) pulse in the Aqueduct of Sylvius (aCSF pulse) is often used to evaluate structural changes in the brain. Here we present a novel application of the general linear model (GLM) to predict the motion of the aCSF pulse.
Clive B Beggs +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source