Results 111 to 120 of about 8,173,281 (311)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Population health profile of the NSW Outback Division of General Practice: supplement [PDF]

, 2007
© Commonwealth of Australia To view the data presented in the profiles in Excel spreadsheets or via Interactive Mapping, please see the PHIDU website at: www.publichealth.gov ...
Ambrose, S., Glover, J., Hutchison, A., Leahy, K.   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

‘I’ve put diabetes completely on the shelf till the mental stuff is in place’. How patients with doctor-assessed impaired self-care perceive disease, self-care, and support from general practitioners. A qualitative study

Scandinavian Journal of Primary Health Care, 2018
Objective: This paper investigated patients’ experiences of disease and self-care as well as perceptions of the general practitioner’s role in supporting patients with impaired self-care ability.
Mads Aage Toft Kristensen, Ann Dorrit Guassora, Anne Beiter Arreskov, Frans Boch Waldorff, Bibi Hølge-Hazelton   +4 more
doaj   +1 more source

Circuits of power : a study of the development of computer software and its use in general medical practice : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Sociology at Massey University [PDF]

, 2000
This thesis explores several phases in the life history of a software package developed in New Zealand for the primary healthcare market in order to show how the package is implicated in maintaining or changing existing distributions of power.
Cornford, Elizabeth Phillipa
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

General Practice Teachers [PDF]

Medical Teacher, 2012
Robert, Moorhead, Tom, Brett, Diane, Arnold-Reed, Maria, Saldanha   +3 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Implementation and acceptability of the Caregiver Care Model in general practice: a mixed-method feasibility study

BMC Primary Care
Background Being a caregiver can be demanding. Therefore, we developed the Caregiver Care Model for general practice. The model consists of a mandatory dialogue questionnaire, which is used to identify support needs in caregivers, grief-facilitating ...
Mette Kjaergaard Nielsen, Marie Cecilie Vinther, Mai-Britt Guldin, Kaj Sparle Christensen, Anna Mygind   +4 more
doaj   +1 more source

Teaching "general practice".

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1967
Click on the link to view.
openaire   +2 more sources