Results 111 to 120 of about 16,433,437 (314)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Shoulder disorders in general practice: Prognostic indicators of outcome

open access: yes, 1996
Background. Shoulder pain is common in primary health care. Nevertheless, information on the outcome of shoulder disorders is scarce, especially for patients encountered in general practice. Aim.
De Jong, Bareld A.   +5 more
core  

Core Values and Principles of Nordic General Practice/Family Medicine

open access: yesScandinavian Journal of Primary Health Care, 2020
Nordic Federation of General Practice (NFGP)
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Getting evidence into practice using an asthma desktop tool

open access: yes, 2006
BACKGROUND: Failure to utilise evidence in asthma care is leading to avoidable asthma symptoms for sufferers and costs to health services. OBJECTIVE: This article describes a collaboration between a division of general practice and a university ...
Campbell, John Patrick   +2 more
core  

The role of nurses in general practice: general practitioners' and practice nurses' perceptions [PDF]

open access: yes, 2004
The role of nurses in general practice: General Practitioners' and Practice Nurses' perceptions is a study that identifies the beliefs of Practice Nurses (PNs) and General Practitioners (GPs) of the PN role and how those roles impact on the general ...
Rees, Sharon
core  

Patterns and Adherence to GOLD-Recommended Inhaled Therapy in Chronic Obstructive Pulmonary Disease (COPD) Patients with Acute Exacerbation History in Primary Care in China

open access: yesInternational Journal of COPD
Hongjing Pei,1 Yujing Su,1 Guanning Jing,1,2 Qiaoli Su,3 Jiao Xu,4 Xue Jin,1 Jingyu Hao,1 Jiapei Xu,1 Jianhua Chen,1 Xueying Li,5 Jing Ma,6 Ying Wang,1 Jingyi Ye,1 Mi Yao,1,2 Chunhua Chi1,2,7,8 1Department of General Practice, Peking University First ...
Pei H   +14 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Twenty-two years of HIV-related consultations in Dutch general practice: a dynamic cohort study.

open access: yes, 2013
Objectives: To examine the role of general practitioners (GPs) in HIV counselling and testing over a 22-year period. Design: A dynamic cohort study. Setting: General practices (N=42) participating in the Dutch Sentinel General Practice Network at Nivel
Donker, G. A.   +7 more
core  

Diagnostic Value of Bilateral Pectoralis Major Total Cross-Sectional Area in Patients with AECOPD Complicated by Malnutrition

open access: yesInternational Journal of COPD
Qin Lu,1,* Lu Wang,2,* Dong Pei,1 Xianqin Jiang,1 Lu Liu,1 Longfei Yue1 1Department of General Medicine, People’s Hospital of Anshun, Guizhou, People’s Republic of China; 2Department of Medical Imaging, People’s Hospital of Anshun ...
Lu Q   +5 more
doaj  

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