Results 171 to 180 of about 6,536,250 (365)

General Relativity

open access: yes, 2015
33 pages, 1 ...
Canuto, V., Goldman, I.
openaire   +2 more sources

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto   +5 more
wiley   +1 more source

Quantum Gravity in Everyday Life: General Relativity as an Effective Field Theory

open access: yesLiving Reviews in Relativity, 2004
This article is meant as a summary and introduction to the ideas of effective field theory as applied to gravitational systems, ideas which provide the theoretical foundations for the modern use of general relativity as a theory from which precise ...
Burgess Cliff P.
doaj  

Horizon phase spaces in general relativity

open access: yesJournal of High Energy Physics
We derive a prescription for the phase space of general relativity on two intersecting null surfaces using the null initial value formulation. The phase space allows generic smooth initial data, and the corresponding boundary symmetry group is the ...
Venkatesa Chandrasekaran   +1 more
doaj   +1 more source

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